SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xou'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1xou ESPA
Z5138 GENE PRODUCT
(Escherichia
coli) 		5 / 12 LEU A  35
THR A 184
ASP A  31
LEU B  55
LEU B  58
 None
 1.42A 3g1uA-1xouA:
undetectable		 3g1uA-1xouA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1xou ESPA
Z5138 GENE PRODUCT
(Escherichia
coli;
Escherichia
coli) 		5 / 12 ILE B  28
ALA A  44
LEU B  75
PHE A  42
ILE B  24
 None
 1.14A 4ptjA-1xouB:
undetectable		 4ptjA-1xouB:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1xou ESPA
Z5138 GENE PRODUCT
(Escherichia
coli) 		5 / 12 THR A 166
GLU B  20
ILE B  17
PHE A  42
ILE A  46
 None
 1.25A 4zvmA-1xouA:
undetectable
4zvmB-1xouA:
undetectable		 4zvmA-1xouA:
21.29
4zvmB-1xouA:
21.29