SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 1xov PLY PROTEIN
(Listeria
virus
PSA) 		3 / 3 TRP A 267
ARG A  40
THR A 270
 None
 0.90A 1df7A-1xovA:
undetectable		 1df7A-1xovA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1xov PLY PROTEIN
(Listeria
virus
PSA) 		4 / 7 VAL A 138
VAL A  88
ILE A 167
ARG A 100
 None
 1.23A 3ms9B-1xovA:
undetectable		 3ms9B-1xovA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 1xov PLY PROTEIN
(Listeria
virus
PSA) 		4 / 6 ILE A  49
ASP A  19
GLY A  16
VAL A 142
 None
None
GLU  A2001 ( 3.7A)
None
 0.94A 3n3iA-1xovA:
undetectable		 3n3iA-1xovA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1xov PLY PROTEIN
(Listeria
virus
PSA) 		4 / 5 ILE A  49
ASP A  36
GLU A  28
VAL A  78
 None
 1.15A 4nkxC-1xovA:
undetectable		 4nkxC-1xovA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1xov PLY PROTEIN
(Listeria
virus
PSA) 		3 / 3 SER A 185
ALA A 187
VAL A 188
 None
 0.32A 4o2bA-1xovA:
4.2		 4o2bA-1xovA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1xov PLY PROTEIN
(Listeria
virus
PSA) 		3 / 3 SER A 185
ALA A 187
VAL A 188
 None
 0.41A 4o2bC-1xovA:
3.9		 4o2bC-1xovA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1xov PLY PROTEIN
(Listeria
virus
PSA) 		3 / 3 SER A 185
ALA A 187
VAL A 188
 None
 0.43A 4x1iA-1xovA:
undetectable		 4x1iA-1xovA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1xov PLY PROTEIN
(Listeria
virus
PSA) 		3 / 3 SER A 185
ALA A 187
VAL A 188
 None
 0.39A 5eypA-1xovA:
3.8		 5eypA-1xovA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1xov PLY PROTEIN
(Listeria
virus
PSA) 		4 / 8 LEU A  21
LEU A 163
TYR A 160
ALA A 153
 None
 0.81A 5f1aA-1xovA:
undetectable		 5f1aA-1xovA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1xov PLY PROTEIN
(Listeria
virus
PSA) 		4 / 5 ILE A 106
LEU A  31
HIS A  75
VAL A  74
 None
 1.19A 5jmnB-1xovA:
undetectable		 5jmnB-1xovA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1xov PLY PROTEIN
(Listeria
virus
PSA) 		3 / 3 LYS A 253
ASP A 247
ILE A 235
 None
 0.75A 5kc4E-1xovA:
undetectable		 5kc4E-1xovA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 1xov PLY PROTEIN
(Listeria
virus
PSA) 		3 / 3 ALA A 153
VAL A  30
TYR A 160
 None
 0.55A 5zmqH-1xovA:
undetectable		 5zmqH-1xovA:
19.11