SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xpg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4F_C_ADNC603_1 (S-ADENOSYLHOMOCYSTEI NE HYDROLASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	HIS A 460 THR A 511 ASP A 577 GLY A 528 PHE A 472	None	1.33A	1d4fC-1xpgA: undetectable	1d4fC-1xpgA: 19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HRK_A_CHDA1503_0 (FERROCHELATASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	LEU A 693 PRO A 694 LEU A 697	None	0.52A	1hrkA-1xpgA: undetectable	1hrkA-1xpgA: 18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_B_SAMB200_0 (METHIONINE REPRESSOR)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 11	GLU A 200 GLY A 149 LEU A 188 LEU A 227 PRO A 226	None	1.14A	1mjqA-1xpgA: undetectable 1mjqB-1xpgA: undetectable	1mjqA-1xpgA: 11.29 1mjqB-1xpgA: 11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT5_A_DVAA6_0 (GRAMICIDIN A)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	ALA A 202 VAL A 236 TRP A 212	None	0.85A	1nt5A-1xpgA: undetectable	1nt5A-1xpgA: 2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT5_B_DVAB6_0 (GRAMICIDIN A)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	ALA A 202 VAL A 236 TRP A 212	None	0.85A	1nt5B-1xpgA: undetectable	1nt5B-1xpgA: 2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_F_BEZF511_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 5	TYR A 232 GLU A 200 PHE A 106 ALA A 202	None None MRY A1890 (-3.7A) None	1.42A	1oniE-1xpgA: 0.7 1oniF-1xpgA: 0.0	1oniE-1xpgA: 11.99 1oniF-1xpgA: 11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_I_BEZI517_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	TYR A 232 ILE A 148 PHE A 106 ALA A 202	None None MRY A1890 (-3.7A) None	1.12A	1oniG-1xpgA: undetectable 1oniI-1xpgA: undetectable	1oniG-1xpgA: 11.99 1oniI-1xpgA: 11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P7R_A_NCTA440_1 (CYTOCHROME P450-CAM)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	PHE A 203 VAL A 247 VAL A 218 ILE A 215	None	1.01A	1p7rA-1xpgA: undetectable	1p7rA-1xpgA: 19.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1U1J_A_C2FA773_0 (5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 8	ARG A 15 LYS A 18 ASN A 109 HIS A 111 SER A 489 ARG A 493 TRP A 539	C2F A1882 ( 4.6A) C2F A1882 (-2.4A) C2F A1882 (-3.7A) None C2F A1882 (-3.0A) C2F A1882 ( 3.5A) C2F A1882 (-3.7A)	0.86A	1u1jA-1xpgA: 47.5	1u1jA-1xpgA: 41.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_E_TFPE212_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	LEU A 488 PHE A 34 MET A 38 MET A 43	None	0.95A	1wrlE-1xpgA: undetectable	1wrlE-1xpgA: 7.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XPG_A_C2FA1882_0 (5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	9 / 9	LYS A 18 LYS A 104 ASN A 109 ASP A 467 SER A 489 ARG A 493 CYH A 494 TRP A 539 GLU A 583	C2F A1882 (-2.4A) C2F A1882 ( 3.3A) C2F A1882 (-3.7A) C2F A1882 ( 4.9A) C2F A1882 (-3.0A) C2F A1882 ( 3.5A) C2F A1882 (-4.6A) C2F A1882 (-3.7A) C2F A1882 (-3.0A)	0.06A	1xpgA-1xpgA: 68.9	1xpgA-1xpgA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XPG_B_C2FB1883_0 (5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	10 / 10	ARG A 15 LYS A 18 LYS A 104 THR A 466 TRP A 486 SER A 489 ARG A 493 CYH A 494 TRP A 539 GLU A 583	C2F A1882 ( 4.6A) C2F A1882 (-2.4A) C2F A1882 ( 3.3A) None None C2F A1882 (-3.0A) C2F A1882 ( 3.5A) C2F A1882 (-4.6A) C2F A1882 (-3.7A) C2F A1882 (-3.0A)	0.47A	1xpgB-1xpgA: 65.6	1xpgB-1xpgA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XR2_A_C2FA1200_0 (5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	9 / 9	ARG A 15 LYS A 18 LYS A 104 SER A 489 ARG A 493 CYH A 494 TRP A 539 PRO A 579 GLU A 583	C2F A1882 ( 4.6A) C2F A1882 (-2.4A) C2F A1882 ( 3.3A) C2F A1882 (-3.0A) C2F A1882 ( 3.5A) C2F A1882 (-4.6A) C2F A1882 (-3.7A) None C2F A1882 (-3.0A)	0.47A	1xr2A-1xpgA: 65.4	1xr2A-1xpgA: 99.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1XR2_B_C2FB1201_0 (5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	8 / 8	LYS A 18 LYS A 104 THR A 466 TRP A 486 SER A 489 ARG A 493 TRP A 539 GLU A 583	C2F A1882 (-2.4A) C2F A1882 ( 3.3A) None None C2F A1882 (-3.0A) C2F A1882 ( 3.5A) C2F A1882 (-3.7A) C2F A1882 (-3.0A)	0.73A	1xr2B-1xpgA: 64.2	1xr2B-1xpgA: 99.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A1O_A_CAMA1422_0 (CYTOCHROME P450-CAM)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 8	LEU A 530 VAL A 574 GLY A 528 ASP A 565	None	0.90A	2a1oA-1xpgA: undetectable	2a1oA-1xpgA: 19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A3A_A_TEPA1436_1 (CHITINASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	ASP A 545 PHE A 361 ARG A 543	None	0.89A	2a3aA-1xpgA: 7.1	2a3aA-1xpgA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CC8_A_RBFA1067_1 (VNG1446H)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	PHE A 412 VAL A 714 TRP A 711	None	0.77A	2cc8A-1xpgA: undetectable	2cc8A-1xpgA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CCB_A_RBFA1067_1 (VNG1446H)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	PHE A 412 VAL A 714 TRP A 711	None	0.77A	2ccbA-1xpgA: undetectable	2ccbA-1xpgA: 7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2D55_C_DVAC8_0 (ACTINOMYCIN D)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	PRO A 579 THR A 531 PRO A 533	None	0.79A	2d55C-1xpgA: undetectable	2d55C-1xpgA: 1.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H42_B_VIAB902_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	ASN A 601 ILE A 631 ALA A 607 ILE A 576 PHE A 581	None	1.06A	2h42B-1xpgA: undetectable	2h42B-1xpgA: 19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PNC_A_CLUA808_1 (COPPER AMINE OXIDASE, LIVER ISOZYME)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	TYR A 90 TYR A 64 MET A 102 TYR A 110	None	1.47A	2pncA-1xpgA: undetectable	2pncA-1xpgA: 21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD3_A_CHDA502_0 (FERROCHELATASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 8	PRO A 115 SER A 157 VAL A 72 GLY A 75	None	1.04A	2qd3A-1xpgA: undetectable	2qd3A-1xpgA: 18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD5_A_CHDA701_0 (FERROCHELATASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 8	PRO A 115 SER A 157 VAL A 72 GLY A 75	None	1.00A	2qd5A-1xpgA: undetectable	2qd5A-1xpgA: 18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VX9_A_RBFA1064_1 (DODECIN)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	PHE A 412 VAL A 714 TRP A 711	None	0.77A	2vx9A-1xpgA: undetectable	2vx9A-1xpgA: 6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AX7_B_SALB1336_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 9	ARG A 384 VAL A 574 LEU A 530 ALA A 606 ALA A 607	None	1.40A	3ax7B-1xpgA: 2.3	3ax7B-1xpgA: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_F_TRPF1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 9	GLY A 665 GLN A 663 VAL A 638 HIS A 616 ILE A 409	None	1.40A	3fi0F-1xpgA: undetectable	3fi0F-1xpgA: 18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3I45_A_NIOA500_1 (TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL PROTEIN)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 8	GLU A 265 LEU A 261 TYR A 239 LEU A 300	None	0.95A	3i45A-1xpgA: undetectable	3i45A-1xpgA: 19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3I5U_B_SAMB401_1 (O-METHYLTRANSFERASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	ASP A 65 PHE A 105 SER A 157	None	1.01A	3i5uB-1xpgA: undetectable	3i5uB-1xpgA: 18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_B_DX4B270_0 (PTERIDINE REDUCTASE 1)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 6	PHE A 105 ASP A 65 TYR A 110 PRO A 201	None	1.45A	3jqaB-1xpgA: 2.5	3jqaB-1xpgA: 17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LTW_A_HLZA300_1 (ARYLAMINE N-ACETYLTRANSFERASE NAT)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 6	PHE A 66 TYR A 112 THR A 152 PHE A 105	None	1.35A	3ltwA-1xpgA: undetectable	3ltwA-1xpgA: 16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NY4_A_SMXA309_1 (BETA-LACTAMASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 5	ILE A 559 ARG A 465 THR A 511 GLU A 462	None	1.36A	3ny4A-1xpgA: undetectable	3ny4A-1xpgA: 16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NY4_A_SMXA309_1 (BETA-LACTAMASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 5	ILE A 571 ARG A 465 THR A 511 GLU A 464	None	1.32A	3ny4A-1xpgA: undetectable	3ny4A-1xpgA: 16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RR3_C_FLRC700_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	VAL A 198 VAL A 218 LEU A 174 TYR A 181 LEU A 222	None	0.96A	3rr3C-1xpgA: undetectable	3rr3C-1xpgA: 21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RR3_D_FLRD700_1 (PROSTAGLANDIN G/H SYNTHASE 2)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	VAL A 198 VAL A 218 LEU A 174 TYR A 181 LEU A 222	None	0.96A	3rr3D-1xpgA: undetectable	3rr3D-1xpgA: 21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E3H_A_HQEA303_1 (CARBONIC ANHYDRASE 2)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 10	VAL A 198 PHE A 185 LEU A 227 VAL A 229 VAL A 247	None	0.97A	4e3hA-1xpgA: undetectable	4e3hA-1xpgA: 16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ENH_A_FVXA602_1 (CHOLESTEROL 24-HYDROXYLASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	LEU A 476 ILE A 479 ILE A 555 THR A 531 ALA A 473	None	0.99A	4enhA-1xpgA: 0.0	4enhA-1xpgA: 20.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4L64_A_C2FA802_0 (5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 7	LYS A 18 TRP A 486 SER A 489 TYR A 490 ARG A 493 TRP A 539	C2F A1882 (-2.4A) None C2F A1882 (-3.0A) None C2F A1882 ( 3.5A) C2F A1882 (-3.7A)	0.49A	4l64A-1xpgA: 49.6	4l64A-1xpgA: 42.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4L65_A_C2FA802_0 (5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 9	LYS A 18 ASP A 467 SER A 489 TYR A 490 ARG A 493	C2F A1882 (-2.4A) C2F A1882 ( 4.9A) C2F A1882 (-3.0A) None C2F A1882 ( 3.5A)	0.79A	4l65A-1xpgA: 49.6	4l65A-1xpgA: 42.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4L65_A_C2FA802_0 (5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 9	LYS A 18 SER A 489 TYR A 490 ARG A 493 TRP A 539	C2F A1882 (-2.4A) C2F A1882 (-3.0A) None C2F A1882 ( 3.5A) C2F A1882 (-3.7A)	0.72A	4l65A-1xpgA: 49.6	4l65A-1xpgA: 42.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4L6H_A_MTXA803_1 (5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 10	LYS A 18 ASP A 467 TRP A 486 SER A 489 PRO A 498	C2F A1882 (-2.4A) C2F A1882 ( 4.9A) None C2F A1882 (-3.0A) None	0.82A	4l6hA-1xpgA: 50.0	4l6hA-1xpgA: 42.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4L6H_A_MTXA803_1 (5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 10	LYS A 18 TRP A 486 SER A 489 PRO A 498 TRP A 539	C2F A1882 (-2.4A) None C2F A1882 (-3.0A) None C2F A1882 (-3.7A)	0.51A	4l6hA-1xpgA: 50.0	4l6hA-1xpgA: 42.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LNW_A_T3A502_1 (THYROID HORMONE RECEPTOR ALPHA)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 8	SER A 88 GLU A 31 MET A 73 VAL A 72	None	1.10A	4lnwA-1xpgA: undetectable	4lnwA-1xpgA: 15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MA7_A_P2ZA301_1 (MAJOR PRION PROTEIN)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 8	VAL A 218 LEU A 222 ILE A 196 THR A 70	None	0.93A	4ma7A-1xpgA: undetectable	4ma7A-1xpgA: 10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_B_C2FB4000_0 (DIHYDROPTEROATE SYNTHASE DHPS)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	ASN A 625 ILE A 664 LEU A 693 GLY A 648 ILE A 650	None	1.12A	4o1eB-1xpgA: 3.5	4o1eB-1xpgA: 16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW0_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	THR A 511 ALA A 473 MET A 529 THR A 531	None	0.78A	4qw0K-1xpgA: undetectable	4qw0K-1xpgA: 13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW0_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	THR A 511 ALA A 473 MET A 529 THR A 531	None	0.78A	4qw0Y-1xpgA: undetectable	4qw0Y-1xpgA: 13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_B_BQ1B1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 8	ALA A 3 ILE A 305 GLU A 350 PHE A 348 LEU A 345	None	1.23A	4v1fA-1xpgA: undetectable 4v1fB-1xpgA: undetectable	4v1fA-1xpgA: 8.53 4v1fB-1xpgA: 8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESH_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	ALA A 210 PHE A 185 ILE A 196 THR A 70 PHE A 203	None	1.20A	5eshA-1xpgA: undetectable	5eshA-1xpgA: 23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OM3_B_DXTB501_1 (ALPHA-1-ANTICHYMOTRY PSIN)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 6	LEU A 87 SER A 88 PHE A 91 ASP A 92	None	0.97A	5om3A-1xpgA: undetectable 5om3B-1xpgA: undetectable	5om3A-1xpgA: 7.43 5om3B-1xpgA: 4.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6ESM_A_PZEA307_1 (MATRIX METALLOPROTEINASE-9, MATRIX METALLOPROTEINASE-9)	1xpg	5-METHYLTETRAHYDROPT EROYLTRIGLUTAMATE--H OMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	TYR A 232 HIS A 251 PHE A 6	None	0.53A	6esmA-1xpgA: undetectable	6esmA-1xpgA: 7.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1D4F_C_ADNC603_1","S-ADENOSYLHOMOCYSTEINE HYDROLASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"HIS A 460;THR A 511;ASP A 577;GLY A 528;PHE A 472","None","1.33A","1d4fC-1xpgA:undetectable","1d4fC-1xpgA:19.84"],["1HRK_A_CHDA1503_0","FERROCHELATASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"LEU A 693;PRO A 694;LEU A 697","None","0.52A","1hrkA-1xpgA:undetectable","1hrkA-1xpgA:18.54"],["1MJQ_B_SAMB200_0","METHIONINE REPRESSOR","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"GLU A 200;GLY A 149;LEU A 188;LEU A 227;PRO A 226","None","1.14A","1mjqA-1xpgA:undetectable;1mjqB-1xpgA:undetectable","1mjqA-1xpgA:11.29;1mjqB-1xpgA:11.29"],["1NT5_A_DVAA6_0","GRAMICIDIN A","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"ALA A 202;VAL A 236;TRP A 212","None","0.85A","1nt5A-1xpgA:undetectable","1nt5A-1xpgA:2.49"],["1NT5_B_DVAB6_0","GRAMICIDIN A","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"ALA A 202;VAL A 236;TRP A 212","None","0.85A","1nt5B-1xpgA:undetectable","1nt5B-1xpgA:2.49"],["1ONI_F_BEZF511_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"TYR A 232;GLU A 200;PHE A 106;ALA A 202","None;None;MRY A1890 (-3.7A);None","1.42A","1oniE-1xpgA:0.7;1oniF-1xpgA:0.0","1oniE-1xpgA:11.99;1oniF-1xpgA:11.99"],["1ONI_I_BEZI517_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"TYR A 232;ILE A 148;PHE A 106;ALA A 202","None;None;MRY A1890 (-3.7A);None","1.12A","1oniG-1xpgA:undetectable;1oniI-1xpgA:undetectable","1oniG-1xpgA:11.99;1oniI-1xpgA:11.99"],["1P7R_A_NCTA440_1","CYTOCHROME P450-CAM","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"PHE A 203;VAL A 247;VAL A 218;ILE A 215","None","1.01A","1p7rA-1xpgA:undetectable","1p7rA-1xpgA:19.30"],["1U1J_A_C2FA773_0","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"ARG A  15;LYS A  18;ASN A 109;HIS A 111;SER A 489;ARG A 493;TRP A 539","C2F A1882 ( 4.6A);C2F A1882 (-2.4A);C2F A1882 (-3.7A);None;C2F A1882 (-3.0A);C2F A1882 ( 3.5A);C2F A1882 (-3.7A)","0.86A","1u1jA-1xpgA:47.5","1u1jA-1xpgA:41.99"],["1WRL_E_TFPE212_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"LEU A 488;PHE A  34;MET A  38;MET A  43","None","0.95A","1wrlE-1xpgA:undetectable","1wrlE-1xpgA:7.97"],["1XPG_A_C2FA1882_0","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",9,"LYS A  18;LYS A 104;ASN A 109;ASP A 467;SER A 489;ARG A 493;CYH A 494;TRP A 539;GLU A 583","C2F A1882 (-2.4A);C2F A1882 ( 3.3A);C2F A1882 (-3.7A);C2F A1882 ( 4.9A);C2F A1882 (-3.0A);C2F A1882 ( 3.5A);C2F A1882 (-4.6A);C2F A1882 (-3.7A);C2F A1882 (-3.0A)","0.06A","1xpgA-1xpgA:68.9","1xpgA-1xpgA:100.00"],["1XPG_B_C2FB1883_0","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",10,"ARG A  15;LYS A  18;LYS A 104;THR A 466;TRP A 486;SER A 489;ARG A 493;CYH A 494;TRP A 539;GLU A 583","C2F A1882 ( 4.6A);C2F A1882 (-2.4A);C2F A1882 ( 3.3A);None;None;C2F A1882 (-3.0A);C2F A1882 ( 3.5A);C2F A1882 (-4.6A);C2F A1882 (-3.7A);C2F A1882 (-3.0A)","0.47A","1xpgB-1xpgA:65.6","1xpgB-1xpgA:100.00"],["1XR2_A_C2FA1200_0","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",9,"ARG A  15;LYS A  18;LYS A 104;SER A 489;ARG A 493;CYH A 494;TRP A 539;PRO A 579;GLU A 583","C2F A1882 ( 4.6A);C2F A1882 (-2.4A);C2F A1882 ( 3.3A);C2F A1882 (-3.0A);C2F A1882 ( 3.5A);C2F A1882 (-4.6A);C2F A1882 (-3.7A);None;C2F A1882 (-3.0A)","0.47A","1xr2A-1xpgA:65.4","1xr2A-1xpgA:99.87"],["1XR2_B_C2FB1201_0","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",8,"LYS A  18;LYS A 104;THR A 466;TRP A 486;SER A 489;ARG A 493;TRP A 539;GLU A 583","C2F A1882 (-2.4A);C2F A1882 ( 3.3A);None;None;C2F A1882 (-3.0A);C2F A1882 ( 3.5A);C2F A1882 (-3.7A);C2F A1882 (-3.0A)","0.73A","1xr2B-1xpgA:64.2","1xr2B-1xpgA:99.87"],["2A1O_A_CAMA1422_0","CYTOCHROME P450-CAM","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"LEU A 530;VAL A 574;GLY A 528;ASP A 565","None","0.90A","2a1oA-1xpgA:undetectable","2a1oA-1xpgA:19.18"],["2A3A_A_TEPA1436_1","CHITINASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"ASP A 545;PHE A 361;ARG A 543","None","0.89A","2a3aA-1xpgA:7.1","2a3aA-1xpgA:20.23"],["2CC8_A_RBFA1067_1","VNG1446H","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"PHE A 412;VAL A 714;TRP A 711","None","0.77A","2cc8A-1xpgA:undetectable","2cc8A-1xpgA:7.07"],["2CCB_A_RBFA1067_1","VNG1446H","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"PHE A 412;VAL A 714;TRP A 711","None","0.77A","2ccbA-1xpgA:undetectable","2ccbA-1xpgA:7.07"],["2D55_C_DVAC8_0","ACTINOMYCIN D","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"PRO A 579;THR A 531;PRO A 533","None","0.79A","2d55C-1xpgA:undetectable","2d55C-1xpgA:1.47"],["2H42_B_VIAB902_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ASN A 601;ILE A 631;ALA A 607;ILE A 576;PHE A 581","None","1.06A","2h42B-1xpgA:undetectable","2h42B-1xpgA:19.09"],["2PNC_A_CLUA808_1","COPPER AMINE OXIDASE, LIVER ISOZYME","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"TYR A  90;TYR A  64;MET A 102;TYR A 110","None","1.47A","2pncA-1xpgA:undetectable","2pncA-1xpgA:21.23"],["2QD3_A_CHDA502_0","FERROCHELATASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"PRO A 115;SER A 157;VAL A  72;GLY A  75","None","1.04A","2qd3A-1xpgA:undetectable","2qd3A-1xpgA:18.41"],["2QD5_A_CHDA701_0","FERROCHELATASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"PRO A 115;SER A 157;VAL A  72;GLY A  75","None","1.00A","2qd5A-1xpgA:undetectable","2qd5A-1xpgA:18.41"],["2VX9_A_RBFA1064_1","DODECIN","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"PHE A 412;VAL A 714;TRP A 711","None","0.77A","2vx9A-1xpgA:undetectable","2vx9A-1xpgA:6.12"],["3AX7_B_SALB1336_1","XANTHINE DEHYDROGENASE\/OXIDASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ARG A 384;VAL A 574;LEU A 530;ALA A 606;ALA A 607","None","1.40A","3ax7B-1xpgA:2.3","3ax7B-1xpgA:20.68"],["3FI0_F_TRPF1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"GLY A 665;GLN A 663;VAL A 638;HIS A 616;ILE A 409","None","1.40A","3fi0F-1xpgA:undetectable","3fi0F-1xpgA:18.95"],["3I45_A_NIOA500_1","TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL PROTEIN","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"GLU A 265;LEU A 261;TYR A 239;LEU A 300","None","0.95A","3i45A-1xpgA:undetectable","3i45A-1xpgA:19.51"],["3I5U_B_SAMB401_1","O-METHYLTRANSFERASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"ASP A  65;PHE A 105;SER A 157","None","1.01A","3i5uB-1xpgA:undetectable","3i5uB-1xpgA:18.29"],["3JQA_B_DX4B270_0","PTERIDINE REDUCTASE 1","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"PHE A 105;ASP A  65;TYR A 110;PRO A 201","None","1.45A","3jqaB-1xpgA:2.5","3jqaB-1xpgA:17.31"],["3LTW_A_HLZA300_1","ARYLAMINE N-ACETYLTRANSFERASE NAT","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"PHE A  66;TYR A 112;THR A 152;PHE A 105","None","1.35A","3ltwA-1xpgA:undetectable","3ltwA-1xpgA:16.93"],["3NY4_A_SMXA309_1","BETA-LACTAMASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"ILE A 559;ARG A 465;THR A 511;GLU A 462","None","1.36A","3ny4A-1xpgA:undetectable","3ny4A-1xpgA:16.33"],["3NY4_A_SMXA309_1","BETA-LACTAMASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"ILE A 571;ARG A 465;THR A 511;GLU A 464","None","1.32A","3ny4A-1xpgA:undetectable","3ny4A-1xpgA:16.33"],["3RR3_C_FLRC700_1","PROSTAGLANDIN G\/H SYNTHASE 2","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"VAL A 198;VAL A 218;LEU A 174;TYR A 181;LEU A 222","None","0.96A","3rr3C-1xpgA:undetectable","3rr3C-1xpgA:21.86"],["3RR3_D_FLRD700_1","PROSTAGLANDIN G\/H SYNTHASE 2","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"VAL A 198;VAL A 218;LEU A 174;TYR A 181;LEU A 222","None","0.96A","3rr3D-1xpgA:undetectable","3rr3D-1xpgA:21.86"],["4E3H_A_HQEA303_1","CARBONIC ANHYDRASE 2","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"VAL A 198;PHE A 185;LEU A 227;VAL A 229;VAL A 247","None","0.97A","4e3hA-1xpgA:undetectable","4e3hA-1xpgA:16.34"],["4ENH_A_FVXA602_1","CHOLESTEROL 24-HYDROXYLASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"LEU A 476;ILE A 479;ILE A 555;THR A 531;ALA A 473","None","0.99A","4enhA-1xpgA:0.0","4enhA-1xpgA:20.72"],["4L64_A_C2FA802_0","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"LYS A  18;TRP A 486;SER A 489;TYR A 490;ARG A 493;TRP A 539","C2F A1882 (-2.4A);None;C2F A1882 (-3.0A);None;C2F A1882 ( 3.5A);C2F A1882 (-3.7A)","0.49A","4l64A-1xpgA:49.6","4l64A-1xpgA:42.74"],["4L65_A_C2FA802_0","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"LYS A  18;ASP A 467;SER A 489;TYR A 490;ARG A 493","C2F A1882 (-2.4A);C2F A1882 ( 4.9A);C2F A1882 (-3.0A);None;C2F A1882 ( 3.5A)","0.79A","4l65A-1xpgA:49.6","4l65A-1xpgA:42.74"],["4L65_A_C2FA802_0","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"LYS A  18;SER A 489;TYR A 490;ARG A 493;TRP A 539","C2F A1882 (-2.4A);C2F A1882 (-3.0A);None;C2F A1882 ( 3.5A);C2F A1882 (-3.7A)","0.72A","4l65A-1xpgA:49.6","4l65A-1xpgA:42.74"],["4L6H_A_MTXA803_1","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"LYS A  18;ASP A 467;TRP A 486;SER A 489;PRO A 498","C2F A1882 (-2.4A);C2F A1882 ( 4.9A);None;C2F A1882 (-3.0A);None","0.82A","4l6hA-1xpgA:50.0","4l6hA-1xpgA:42.74"],["4L6H_A_MTXA803_1","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"LYS A  18;TRP A 486;SER A 489;PRO A 498;TRP A 539","C2F A1882 (-2.4A);None;C2F A1882 (-3.0A);None;C2F A1882 (-3.7A)","0.51A","4l6hA-1xpgA:50.0","4l6hA-1xpgA:42.74"],["4LNW_A_T3A502_1","THYROID HORMONE RECEPTOR ALPHA","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"SER A  88;GLU A  31;MET A  73;VAL A  72","None","1.10A","4lnwA-1xpgA:undetectable","4lnwA-1xpgA:15.07"],["4MA7_A_P2ZA301_1","MAJOR PRION PROTEIN","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"VAL A 218;LEU A 222;ILE A 196;THR A  70","None","0.93A","4ma7A-1xpgA:undetectable","4ma7A-1xpgA:10.23"],["4O1E_B_C2FB4000_0","DIHYDROPTEROATE SYNTHASE DHPS","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ASN A 625;ILE A 664;LEU A 693;GLY A 648;ILE A 650","None","1.12A","4o1eB-1xpgA:3.5","4o1eB-1xpgA:16.71"],["4QW0_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"THR A 511;ALA A 473;MET A 529;THR A 531","None","0.78A","4qw0K-1xpgA:undetectable","4qw0K-1xpgA:13.67"],["4QW0_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"THR A 511;ALA A 473;MET A 529;THR A 531","None","0.78A","4qw0Y-1xpgA:undetectable","4qw0Y-1xpgA:13.67"],["4V1F_B_BQ1B1087_0","F0F1 ATP SYNTHASE SUBUNIT C","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ALA A   3;ILE A 305;GLU A 350;PHE A 348;LEU A 345","None","1.23A","4v1fA-1xpgA:undetectable;4v1fB-1xpgA:undetectable","4v1fA-1xpgA:8.53;4v1fB-1xpgA:8.53"],["5ESH_A_1YNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ALA A 210;PHE A 185;ILE A 196;THR A  70;PHE A 203","None","1.20A","5eshA-1xpgA:undetectable","5eshA-1xpgA:23.01"],["5OM3_B_DXTB501_1","ALPHA-1-ANTICHYMOTRYPSIN;ALPHA-1-ANTICHYMOTRYPSIN","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"LEU A  87;SER A  88;PHE A  91;ASP A  92","None","0.97A","5om3A-1xpgA:undetectable;5om3B-1xpgA:undetectable","5om3A-1xpgA:7.43;5om3B-1xpgA:4.47"],["6ESM_A_PZEA307_1","MATRIX METALLOPROTEINASE-9,MATRIX METALLOPROTEINASE-9","1xpg","5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"TYR A 232;HIS A 251;PHE A   6","None","0.53A","6esmA-1xpgA:undetectable","6esmA-1xpgA:7.03"]]