SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xpj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 1xpj HYPOTHETICAL PROTEIN
(Vibrio
cholerae) 		3 / 3 PHE A  41
LEU A 112
MET A 110
 None
 0.90A 1mx1D-1xpjA:
undetectable		 1mx1D-1xpjA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1xpj HYPOTHETICAL PROTEIN
(Vibrio
cholerae) 		4 / 7 ARG A  49
ILE A  61
PRO A  67
ILE A  68
 None
 0.98A 4w5oA-1xpjA:
0.0		 4w5oA-1xpjA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1xpj HYPOTHETICAL PROTEIN
(Vibrio
cholerae) 		4 / 7 ARG A  49
ILE A  61
PRO A  67
ILE A  68
 None
 0.95A 4z4eA-1xpjA:
undetectable		 4z4eA-1xpjA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1xpj HYPOTHETICAL PROTEIN
(Vibrio
cholerae) 		4 / 7 ARG A  49
ILE A  61
PRO A  67
ILE A  68
 None
 0.94A 4z4gA-1xpjA:
3.1		 4z4gA-1xpjA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 1xpj HYPOTHETICAL PROTEIN
(Vibrio
cholerae) 		3 / 3 GLY A  10
ASP A   7
ILE A  45
 None
 0.52A 6dgxB-1xpjA:
undetectable		 6dgxB-1xpjA:
22.86