SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xpn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1xpn HYPOTHETICAL PROTEIN
PA1324
(Pseudomonas
aeruginosa) 		4 / 7 ARG A 104
GLU A  32
PRO A  28
ALA A  78
 None
 1.41A 2ejgB-1xpnA:
undetectable		 2ejgB-1xpnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1xpn HYPOTHETICAL PROTEIN
PA1324
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 166
THR A 113
ILE A 131
SER A 133
PHE A 119
 None
 1.14A 2vdyB-1xpnA:
undetectable		 2vdyB-1xpnA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 1xpn HYPOTHETICAL PROTEIN
PA1324
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 107
ASP A 101
HIS A  33
 None
 0.86A 3e23A-1xpnA:
undetectable		 3e23A-1xpnA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1xpn HYPOTHETICAL PROTEIN
PA1324
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  44
GLY A  43
GLY A  42
VAL A 158
VAL A 156
 None
 0.99A 4htfA-1xpnA:
undetectable		 4htfA-1xpnA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1xpn HYPOTHETICAL PROTEIN
PA1324
(Pseudomonas
aeruginosa) 		5 / 9 ALA A  72
ILE A  46
LEU A  69
ILE A 124
ASN A 126
 None
 0.98A 5nunA-1xpnA:
undetectable		 5nunA-1xpnA:
20.96