SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xq4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 1xq4 PROTEIN APAG
(Bordetella
pertussis) 		5 / 11 VAL A  39
TYR A 105
TYR A  88
VAL A  51
PRO A  78
 None
 1.37A 1i9jH-1xq4A:
4.5
1i9jL-1xq4A:
4.3		 1i9jH-1xq4A:
19.91
1i9jL-1xq4A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 1xq4 PROTEIN APAG
(Bordetella
pertussis) 		5 / 12 LEU A  71
GLY A  72
VAL A  68
ILE A  41
VAL A  39
 None
 1.28A 4okwA-1xq4A:
undetectable		 4okwA-1xq4A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 1xq4 PROTEIN APAG
(Bordetella
pertussis) 		4 / 8 ILE A  57
TYR A 105
THR A 104
ILE A 119
 None
None
PO4  A 401 (-3.2A)
None
 0.80A 5mzrE-1xq4A:
3.1		 5mzrE-1xq4A:
20.61