SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ILQ_C_ACAC7_1
(INTERLEUKIN-8
PRECURSOR
INTERLEUKIN-8
RECEPTOR A)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		4 / 6 HIS A 144
ASP A 138
ASP A 135
PRO A 142
 None
 1.39A 1ilqA-1xq9A:
0.0
1ilqC-1xq9A:
undetectable		 1ilqA-1xq9A:
14.51
1ilqC-1xq9A:
5.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		4 / 7 VAL A  78
LEU A  79
ALA A 190
LEU A  17
 None
 0.78A 1pthA-1xq9A:
undetectable		 1pthA-1xq9A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		4 / 7 VAL A  78
LEU A  79
ALA A 190
LEU A  17
 None
 0.78A 1pthB-1xq9A:
undetectable		 1pthB-1xq9A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		4 / 8 ARG A 168
GLU A 160
VAL A 151
TYR A 148
 None
 1.12A 2fl5E-1xq9A:
undetectable
2fl5F-1xq9A:
undetectable		 2fl5E-1xq9A:
20.15
2fl5F-1xq9A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		4 / 6 ARG A  70
TRP A  24
ARG A 140
SER A 102
 None
 1.19A 3ckzA-1xq9A:
undetectable		 3ckzA-1xq9A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		5 / 12 GLU A  45
GLY A  42
GLY A  50
LEU A  17
PRO A 221
 None
 1.31A 4uinH-1xq9A:
undetectable
4uinL-1xq9A:
undetectable		 4uinH-1xq9A:
20.60
4uinL-1xq9A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		4 / 8 TYR A 224
ASP A 204
ILE A 233
TYR A 236
 None
 0.85A 4xjeA-1xq9A:
undetectable		 4xjeA-1xq9A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		4 / 8 TYR A 224
ASP A 204
ILE A 233
TYR A 236
 None
 0.99A 5cfsA-1xq9A:
undetectable		 5cfsA-1xq9A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		4 / 6 VAL A  63
THR A  65
LEU A 238
GLU A 225
 None
 0.90A 5tudD-1xq9A:
undetectable		 5tudD-1xq9A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		5 / 10 LEU A 103
SER A 102
LEU A 134
ASP A 135
PRO A 130
 None
 1.38A 6dlzB-1xq9A:
2.9
6dlzC-1xq9A:
undetectable		 6dlzB-1xq9A:
13.62
6dlzC-1xq9A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		5 / 11 PRO A 130
LEU A 103
SER A 102
LEU A 134
ASP A 135
 None
 1.38A 6dlzA-1xq9A:
undetectable
6dlzD-1xq9A:
undetectable		 6dlzA-1xq9A:
13.62
6dlzD-1xq9A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		5 / 10 LEU A 103
SER A 102
LEU A 134
ASP A 135
PRO A 130
 None
 1.38A 6dm1B-1xq9A:
2.9
6dm1C-1xq9A:
undetectable		 6dm1B-1xq9A:
13.62
6dm1C-1xq9A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		5 / 11 PRO A 130
LEU A 103
SER A 102
LEU A 134
ASP A 135
 None
 1.37A 6dm1A-1xq9A:
undetectable
6dm1D-1xq9A:
undetectable		 6dm1A-1xq9A:
13.62
6dm1D-1xq9A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		5 / 10 LEU A 103
SER A 102
LEU A 134
ASP A 135
PRO A 130
 None
 1.39A 6dm2B-1xq9A:
undetectable
6dm2C-1xq9A:
undetectable		 6dm2B-1xq9A:
13.62
6dm2C-1xq9A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 1xq9 PHOSPHOGLYCERATE
MUTASE
(Plasmodium
falciparum) 		5 / 10 PRO A 130
LEU A 103
SER A 102
LEU A 134
ASP A 135
 None
 1.39A 6dm2A-1xq9A:
undetectable
6dm2D-1xq9A:
3.9		 6dm2A-1xq9A:
13.62
6dm2D-1xq9A:
13.62