SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 1xqb HYPOTHETICAL UPF0066
PROTEIN HI0510
(Haemophilus
influenzae) 		4 / 7 VAL A  36
LEU A  51
VAL A  48
LEU A  59
 None
 0.75A 1cqpA-1xqbA:
undetectable
1cqpB-1xqbA:
undetectable		 1cqpA-1xqbA:
21.16
1cqpB-1xqbA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)		 1xqb HYPOTHETICAL UPF0066
PROTEIN HI0510
(Haemophilus
influenzae) 		5 / 12 TYR A 214
PHE A 186
GLN A 189
VAL A  29
MET A 211
 None
 1.39A 2jj8B-1xqbA:
undetectable		 2jj8B-1xqbA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1xqb HYPOTHETICAL UPF0066
PROTEIN HI0510
(Haemophilus
influenzae) 		4 / 4 LEU A 121
GLY A 122
GLY A  34
THR A  14
 None
 0.95A 3si7A-1xqbA:
undetectable		 3si7A-1xqbA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 1xqb HYPOTHETICAL UPF0066
PROTEIN HI0510
(Haemophilus
influenzae) 		5 / 11 ASP A 134
LEU A  57
LEU A  38
ILE A   9
LEU A 119
 None
 1.01A 4zowA-1xqbA:
undetectable		 4zowA-1xqbA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 1xqb HYPOTHETICAL UPF0066
PROTEIN HI0510
(Haemophilus
influenzae) 		5 / 12 GLY A 122
LEU A 107
SER A  55
VAL A 124
VAL A  36
 None
 1.03A 5dpdA-1xqbA:
undetectable		 5dpdA-1xqbA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 1xqb HYPOTHETICAL UPF0066
PROTEIN HI0510
(Haemophilus
influenzae) 		5 / 12 GLY A 122
LEU A 107
SER A  55
VAL A 124
VAL A  36
 None
 1.04A 5dpdB-1xqbA:
undetectable		 5dpdB-1xqbA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 1xqb HYPOTHETICAL UPF0066
PROTEIN HI0510
(Haemophilus
influenzae) 		3 / 3 VAL A  48
GLN A 109
CYH A 112
 None
 0.72A 5icxC-1xqbA:
0.1
5icxF-1xqbA:
undetectable		 5icxC-1xqbA:
21.74
5icxF-1xqbA:
9.62