SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xqm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		4 / 7 TYR A  72
SER A  83
TYR A 178
GLN A  39
 None
None
None
CH6  A  63 ( 3.5A)
 1.22A 1eiiA-1xqmA:
undetectable		 1eiiA-1xqmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		4 / 6 PHE A  55
GLU A 203
LYS A 207
VAL A 205
 None
 1.38A 1l2iB-1xqmA:
undetectable		 1l2iB-1xqmA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		5 / 12 MET A  41
CYH A  26
ILE A 121
PHE A  24
LEU A  51
 CH6  A  63 ( 3.8A)
None
None
None
None
 1.48A 1m2zD-1xqmA:
undetectable		 1m2zD-1xqmA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		5 / 11 GLY A 219
HIS A 193
GLU A 145
HIS A 197
VAL A 218
 None
None
CH6  A  63 ( 3.3A)
CH6  A  63 ( 3.5A)
None
 1.14A 1pg2A-1xqmA:
undetectable		 1pg2A-1xqmA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		4 / 6 GLU A 215
THR A  13
TYR A 117
TYR A 178
 CH6  A  63 ( 3.0A)
None
CH6  A  63 ( 4.6A)
None
 1.23A 1qvuA-1xqmA:
undetectable		 1qvuA-1xqmA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_B_NCAB901_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		4 / 5 ILE A  76
PRO A 190
PHE A  80
VAL A 147
 None
 1.40A 2hjhB-1xqmA:
undetectable		 2hjhB-1xqmA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		4 / 6 GLU A 195
ASP A  78
TYR A  79
LYS A  81
 None
 1.43A 3pocB-1xqmA:
undetectable		 3pocB-1xqmA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		4 / 6 THR A  14
GLY A  28
ILE A  43
LYS A  66
 None
None
None
CH6  A  63 ( 3.5A)
 1.01A 4acbC-1xqmA:
undetectable		 4acbC-1xqmA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		4 / 5 GLY A  37
ALA A 217
PHE A  69
GLU A 215
 None
None
None
CH6  A  63 ( 3.0A)
 0.93A 4m93B-1xqmA:
undetectable
4m93C-1xqmA:
undetectable		 4m93B-1xqmA:
22.27
4m93C-1xqmA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		3 / 3 PRO A 190
MET A 189
TYR A  79
 None
 0.74A 4qa0B-1xqmA:
undetectable		 4qa0B-1xqmA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		3 / 3 PRO A 190
MET A 189
TYR A  79
 None
 0.76A 4qa0A-1xqmA:
undetectable		 4qa0A-1xqmA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		3 / 3 PRO A 190
MET A 189
TYR A  79
 None
 0.82A 4qa2B-1xqmA:
undetectable		 4qa2B-1xqmA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		4 / 7 ASN A  33
PRO A  34
PHE A  69
TYR A 214
 None
 1.25A 4v2yB-1xqmA:
0.0		 4v2yB-1xqmA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		5 / 11 VAL A 205
PHE A  53
GLY A  49
GLY A  48
ILE A  46
 None
 1.02A 4zvmA-1xqmA:
undetectable
4zvmB-1xqmA:
undetectable		 4zvmA-1xqmA:
21.26
4zvmB-1xqmA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		5 / 12 GLU A 149
VAL A 150
HIS A 197
PHE A  80
GLY A 219
 None
None
CH6  A  63 ( 3.5A)
None
None
 1.14A 5xioA-1xqmA:
undetectable		 5xioA-1xqmA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 1xqm KINDLING FLUORESCENT
PROTEIN
(Anemonia
sulcata) 		5 / 11 ILE A  70
TYR A 178
LEU A 154
GLY A 156
SER A 158
 None
None
None
None
CH6  A  63 ( 2.4A)
 1.19A 6ieyA-1xqmA:
undetectable
6ieyB-1xqmA:
undetectable		 6ieyA-1xqmA:
17.55
6ieyB-1xqmA:
17.55