SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xr5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 THR A  19
PRO A  20
LEU A  58
PHE A 274
 None
 0.81A 1h4oG-1xr5A:
undetectable		 1h4oG-1xr5A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 LEU A 249
VAL A 252
LEU A 256
 None
 0.35A 1mz9B-1xr5A:
undetectable		 1mz9B-1xr5A:
6.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 12 LEU A 419
ALA A 420
PHE A 431
LEU A 446
PRO A 447
 None
 1.20A 1og5A-1xr5A:
undetectable		 1og5A-1xr5A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.03A 1p7lC-1xr5A:
undetectable		 1p7lC-1xr5A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.03A 1p7lD-1xr5A:
undetectable		 1p7lD-1xr5A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.04A 1rg9A-1xr5A:
undetectable		 1rg9A-1xr5A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.04A 1rg9B-1xr5A:
undetectable		 1rg9B-1xr5A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.02A 1rg9C-1xr5A:
undetectable		 1rg9C-1xr5A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.03A 1rg9D-1xr5A:
undetectable		 1rg9D-1xr5A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 VAL A 387
VAL A 216
TRP A 218
 None
 0.98A 1w5uA-1xr5A:
undetectable
1w5uB-1xr5A:
undetectable		 1w5uA-1xr5A:
2.83
1w5uB-1xr5A:
2.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 9 LEU A  50
ARG A  49
LEU A  54
LEU A  58
ALA A  41
 None
 1.27A 2bxeA-1xr5A:
0.4		 2bxeA-1xr5A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 9 LEU A 194
PHE A 198
LEU A 253
LEU A 249
ALA A  82
 None
 1.25A 2bxeA-1xr5A:
0.4		 2bxeA-1xr5A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 LYS A 394
TYR A 376
PRO A 392
 None
 1.45A 2j9cC-1xr5A:
undetectable		 2j9cC-1xr5A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.18A 2obvA-1xr5A:
undetectable		 2obvA-1xr5A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 7 LEU A  85
PHE A 295
PHE A 198
ILE A  90
PHE A 258
 None
 1.43A 2opxA-1xr5A:
undetectable		 2opxA-1xr5A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.18A 2p02A-1xr5A:
undetectable		 2p02A-1xr5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 5 GLN A 340
PHE A 362
PHE A 232
GLY A 346
 None
 1.11A 2qmzA-1xr5A:
undetectable
2qmzB-1xr5A:
undetectable		 2qmzA-1xr5A:
19.40
2qmzB-1xr5A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 7 THR A  19
PRO A  20
LEU A  58
PHE A 274
 None
 0.92A 2vl2B-1xr5A:
undetectable		 2vl2B-1xr5A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 6 ASN A 300
SER A 297
ALA A 324
ASP A 328
 None
None
None
SM  A 901 (-3.0A)
 1.16A 3aruA-1xr5A:
undetectable		 3aruA-1xr5A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 GLY A 149
ASN A 182
PHE A 143
TYR A 148
 None
 1.25A 3ccfA-1xr5A:
undetectable		 3ccfA-1xr5A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 7 TYR A 195
MET A 298
LEU A 194
PHE A 295
 None
 1.28A 3nk2X-1xr5A:
undetectable		 3nk2X-1xr5A:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		6 / 9 ASP A 238
ASN A 296
TYR A 325
GLY A 326
ASP A 327
ASP A 328
 None
None
None
None
SM  A 901 (-2.6A)
SM  A 901 (-3.0A)
 0.82A 3sfuA-1xr5A:
30.7		 3sfuA-1xr5A:
27.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 9 ASP A 238
SER A 287
ASN A 296
ASP A 327
ASP A 328
 None
None
None
SM  A 901 (-2.6A)
SM  A 901 (-3.0A)
 1.21A 3sfuA-1xr5A:
30.7		 3sfuA-1xr5A:
27.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		7 / 9 ASP A 238
ASN A 296
TYR A 325
GLY A 326
ASP A 327
ASP A 328
LEU A 373
 None
None
None
None
SM  A 901 (-2.6A)
SM  A 901 (-3.0A)
None
 0.75A 3sfuB-1xr5A:
30.9		 3sfuB-1xr5A:
27.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 11 ASP A 238
SER A 287
ASN A 296
GLY A 326
ASP A 327
 None
None
None
None
SM  A 901 (-2.6A)
 1.12A 3sfuC-1xr5A:
30.8		 3sfuC-1xr5A:
27.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 6 GLY A 288
ARG A 163
ILE A 176
LEU A 154
 None
 1.23A 4acaC-1xr5A:
undetectable		 4acaC-1xr5A:
23.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 VAL A 121
GLY A 124
LYS A 126
 None
 0.55A 4k50A-1xr5A:
51.8		 4k50A-1xr5A:
55.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 HIS A 199
GLY A 291
ILE A 294
 None
 0.41A 4k50A-1xr5A:
51.8		 4k50A-1xr5A:
55.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 VAL A 121
GLY A 124
LYS A 126
 None
 0.61A 4k50E-1xr5A:
51.9		 4k50E-1xr5A:
55.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 VAL A 121
GLY A 124
LYS A 126
 None
 0.59A 4k50I-1xr5A:
51.9		 4k50I-1xr5A:
55.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 HIS A 199
GLY A 291
ILE A 294
 None
 0.42A 4k50I-1xr5A:
51.9		 4k50I-1xr5A:
55.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 LEU A 256
LEU A 253
LEU A 249
ILE A  90
 None
 0.74A 4klaA-1xr5A:
undetectable		 4klaA-1xr5A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.21A 4kttA-1xr5A:
undetectable		 4kttA-1xr5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.20A 4kttC-1xr5A:
undetectable		 4kttC-1xr5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.23A 4ndnA-1xr5A:
undetectable		 4ndnA-1xr5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 7 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.19A 4ndnC-1xr5A:
undetectable		 4ndnC-1xr5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 7 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.15A 4odjA-1xr5A:
undetectable		 4odjA-1xr5A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 7 GLY A 207
GLN A  84
ARG A 305
ILE A 304
 None
 0.94A 4txnA-1xr5A:
undetectable		 4txnA-1xr5A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 7 GLY A 207
GLN A  84
ARG A 305
ILE A 304
 None
 0.94A 4txnC-1xr5A:
undetectable		 4txnC-1xr5A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 7 GLY A 207
GLN A  84
ARG A 305
ILE A 304
 None
 0.91A 4txnD-1xr5A:
undetectable		 4txnD-1xr5A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.12A 5a1iA-1xr5A:
undetectable		 5a1iA-1xr5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 7 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.12A 5a1iA-1xr5A:
undetectable		 5a1iA-1xr5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
GLY A 424
VAL A 390
HIS A 388
 None
 0.79A 5f8yA-1xr5A:
undetectable		 5f8yA-1xr5A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 12 PRO A 153
GLY A 117
THR A 114
SER A 122
TYR A 120
 None
 1.21A 5hfjB-1xr5A:
undetectable		 5hfjB-1xr5A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 12 PRO A 153
GLY A 117
THR A 114
SER A 122
TYR A 120
 None
 1.29A 5hfjC-1xr5A:
undetectable		 5hfjC-1xr5A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 12 PRO A 153
GLY A 117
THR A 114
SER A 122
TYR A 120
 None
 1.31A 5hfjH-1xr5A:
undetectable		 5hfjH-1xr5A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 THR A  21
PRO A  40
ARG A 163
 None
 0.81A 5nd7B-1xr5A:
undetectable		 5nd7B-1xr5A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 4 LEU A 307
MET A 230
ILE A 302
LEU A 320
 None
 1.33A 5nfpA-1xr5A:
undetectable		 5nfpA-1xr5A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.12A 5t8sB-1xr5A:
undetectable		 5t8sB-1xr5A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 10 TYR A 325
ILE A 304
ILE A 308
LEU A 309
ILE A 299
 None
 1.44A 5vkqA-1xr5A:
undetectable
5vkqD-1xr5A:
undetectable		 5vkqA-1xr5A:
12.78
5vkqD-1xr5A:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 10 ILE A 299
TYR A 325
ILE A 304
ILE A 308
LEU A 309
 None
 1.46A 5vkqA-1xr5A:
0.0
5vkqB-1xr5A:
0.0		 5vkqA-1xr5A:
12.78
5vkqB-1xr5A:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 9 ILE A 299
TYR A 325
ILE A 304
ILE A 308
LEU A 309
 None
 1.45A 5vkqB-1xr5A:
undetectable
5vkqC-1xr5A:
undetectable		 5vkqB-1xr5A:
12.78
5vkqC-1xr5A:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 LEU A 351
THR A  68
ASN A  67
 None
 0.71A 6baaE-1xr5A:
undetectable		 6baaE-1xr5A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 LEU A 351
THR A  68
ASN A  67
 None
 0.71A 6baaF-1xr5A:
undetectable		 6baaF-1xr5A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 LEU A 351
THR A  68
ASN A  67
 None
 0.71A 6baaG-1xr5A:
undetectable		 6baaG-1xr5A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 LEU A 351
THR A  68
ASN A  67
 None
 0.71A 6baaH-1xr5A:
undetectable		 6baaH-1xr5A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		5 / 12 ILE A 150
SER A 290
TYR A 195
ASN A 186
LEU A 181
 None
 1.37A 6chgC-1xr5A:
undetectable		 6chgC-1xr5A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.19A 6fbnB-1xr5A:
undetectable		 6fbnB-1xr5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.15A 6fboA-1xr5A:
undetectable		 6fboA-1xr5A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.21A 6fcbA-1xr5A:
undetectable		 6fcbA-1xr5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 8 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.13A 6fcdA-1xr5A:
undetectable		 6fcdA-1xr5A:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 7 HIS A 422
PRO A 389
PHE A 460
ASP A 215
 None
 1.13A 6g6rA-1xr5A:
undetectable		 6g6rA-1xr5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		4 / 5 GLY A 149
LEU A 145
SER A 180
TYR A 120
 None
 1.27A 6ji6A-1xr5A:
undetectable		 6ji6A-1xr5A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 1xr5 GENOME POLYPROTEIN
(Rhinovirus
B) 		3 / 3 ASP A 215
LEU A 459
ARG A 454
 None
 0.86A 7dfrA-1xr5A:
undetectable		 7dfrA-1xr5A:
16.09