SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xr6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
5 / 11 LEU A 337
VAL A 308
ILE A 322
PHE A 233
MET A 231
None
1.40A 1gx9A-1xr6A:
undetectable
1gx9A-1xr6A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 8 THR A  19
PRO A  20
LEU A  58
PHE A 274
None
0.75A 1h4oG-1xr6A:
undetectable
1h4oG-1xr6A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 6 ASN A 300
ASN A 301
ILE A 323
GLY A 207
None
0.95A 1oniA-1xr6A:
undetectable
1oniB-1xr6A:
undetectable
1oniA-1xr6A:
17.31
1oniB-1xr6A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 6 ASN A 300
ASN A 301
ILE A 323
GLY A 207
None
0.95A 1oniD-1xr6A:
undetectable
1oniF-1xr6A:
undetectable
1oniD-1xr6A:
17.31
1oniF-1xr6A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 7 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.99A 1rxcC-1xr6A:
undetectable
1rxcC-1xr6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 7 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.96A 1rxcD-1xr6A:
undetectable
1rxcD-1xr6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 7 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
1.08A 1rxcF-1xr6A:
undetectable
1rxcF-1xr6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 7 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
1.03A 1rxcL-1xr6A:
undetectable
1rxcL-1xr6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 8 LEU A 351
TYR A 349
ILE A 303
ILE A 299
None
0.73A 2bu8A-1xr6A:
undetectable
2bu8A-1xr6A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 7 ASP A 226
ILE A 322
ASN A 301
GLN A  84
None
1.13A 2jc9A-1xr6A:
undetectable
2jc9A-1xr6A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
3 / 3 TYR A 397
GLY A  36
PHE A  34
None
0.51A 2m2pB-1xr6A:
undetectable
2m2pB-1xr6A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
5 / 12 ILE A 322
THR A 306
LEU A 307
LEU A 351
TYR A 238
None
1.44A 2mjiA-1xr6A:
undetectable
2mjiA-1xr6A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 4 SER A 241
TRP A 246
ASP A 338
ILE A 342
None
1.43A 2oxtD-1xr6A:
undetectable
2oxtD-1xr6A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 7 HIS A 412
VAL A 413
VAL A  29
ALA A 440
None
0.72A 3kp6B-1xr6A:
undetectable
3kp6B-1xr6A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 6 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.98A 3kvvA-1xr6A:
undetectable
3kvvA-1xr6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 6 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.95A 3kvvB-1xr6A:
undetectable
3kvvB-1xr6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 6 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.92A 3kvvC-1xr6A:
undetectable
3kvvC-1xr6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 6 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.94A 3kvvD-1xr6A:
undetectable
3kvvD-1xr6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 6 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.95A 3kvvE-1xr6A:
undetectable
3kvvE-1xr6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 6 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.99A 3kvvF-1xr6A:
undetectable
3kvvF-1xr6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
5 / 12 TYR A 238
PHE A 233
GLY A 346
ILE A 322
ILE A 323
None
1.08A 3ld6A-1xr6A:
undetectable
3ld6A-1xr6A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 6 LEU A 373
PHE A 372
ILE A 323
ALA A 324
None
0.73A 3mdrA-1xr6A:
undetectable
3mdrA-1xr6A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
7 / 9 ASP A 239
SER A 287
ASN A 296
TYR A 325
GLY A 326
ASP A 327
ASP A 328
None
1.11A 3sfuA-1xr6A:
30.9
3sfuA-1xr6A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_B_RBVB601_1
(RNA POLYMERASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
7 / 9 ASP A 239
ASN A 296
TYR A 325
GLY A 326
ASP A 327
ASP A 328
LEU A 373
None
0.59A 3sfuB-1xr6A:
30.9
3sfuB-1xr6A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
5 / 11 ARG A 174
ASP A 239
ASN A 296
GLY A 326
ASP A 327
None
0.87A 3sfuC-1xr6A:
30.9
3sfuC-1xr6A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
5 / 11 ARG A 174
ASP A 239
THR A 292
GLY A 326
ASP A 327
None
0.92A 3sfuC-1xr6A:
30.9
3sfuC-1xr6A:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 8 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.99A 4e1vA-1xr6A:
undetectable
4e1vA-1xr6A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 7 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.98A 4e1vB-1xr6A:
undetectable
4e1vB-1xr6A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 8 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.96A 4e1vC-1xr6A:
undetectable
4e1vC-1xr6A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 8 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.97A 4e1vD-1xr6A:
undetectable
4e1vD-1xr6A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 8 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.99A 4e1vE-1xr6A:
undetectable
4e1vE-1xr6A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 6 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
1.02A 4e1vF-1xr6A:
undetectable
4e1vF-1xr6A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 8 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
0.98A 4e1vH-1xr6A:
undetectable
4e1vH-1xr6A:
20.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
3 / 3 ARG A 163
LYS A 164
LYS A 167
None
1.02A 4k50A-1xr6A:
55.5
4k50A-1xr6A:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
3 / 3 CYH A  68
ASN A  71
LYS A 348
None
0.38A 4k50A-1xr6A:
55.5
4k50A-1xr6A:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
3 / 3 VAL A 121
GLY A 124
LYS A 126
None
0.60A 4k50A-1xr6A:
55.5
4k50A-1xr6A:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
3 / 3 HIS A 199
GLY A 291
ILE A 294
None
0.51A 4k50A-1xr6A:
55.5
4k50A-1xr6A:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_E_ACTE501_0
(RNA POLYMERASE
3D-POL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 4 CYH A 212
THR A 216
PHE A 217
LYS A 220
None
0.32A 4k50E-1xr6A:
55.6
4k50E-1xr6A:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
3 / 3 ARG A 163
LYS A 164
LYS A 167
None
0.97A 4k50E-1xr6A:
55.6
4k50E-1xr6A:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
3 / 3 VAL A 121
GLY A 124
LYS A 126
None
0.50A 4k50E-1xr6A:
55.6
4k50E-1xr6A:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_F_ACTF701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 4 PHE A 195
HIS A 199
GLY A 291
ILE A 294
None
0.46A 4k50E-1xr6A:
55.6
4k50E-1xr6A:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
3 / 3 ARG A 163
LYS A 164
LYS A 167
None
0.99A 4k50I-1xr6A:
49.6
4k50I-1xr6A:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
3 / 3 HIS A 199
GLY A 291
ILE A 294
None
0.51A 4k50I-1xr6A:
49.6
4k50I-1xr6A:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_M_ACTM502_0
(RNA POLYMERASE
3D-POL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 4 CYH A 212
THR A 216
PHE A 217
LYS A 220
None
0.30A 4k50M-1xr6A:
48.9
4k50M-1xr6A:
85.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K50_M_ACTM503_0
(RNA POLYMERASE
3D-POL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 4 PHE A 195
HIS A 199
GLY A 291
ILE A 294
None
0.50A 4k50M-1xr6A:
48.9
4k50M-1xr6A:
85.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 8 LEU A 257
LEU A 254
LEU A 250
ILE A  90
None
0.89A 4klaA-1xr6A:
undetectable
4klaA-1xr6A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
5 / 11 ILE A 299
GLN A 248
PHE A 247
LEU A 250
LEU A 351
None
1.15A 4nqaA-1xr6A:
undetectable
4nqaA-1xr6A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 4 ASN A  71
VAL A 245
THR A 306
ILE A 303
None
1.21A 4retA-1xr6A:
undetectable
4retA-1xr6A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 4 ASN A  71
VAL A 245
THR A 306
ILE A 303
None
1.21A 4retC-1xr6A:
undetectable
4retC-1xr6A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_ACTA502_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 4 LYS A 426
ARG A 425
GLY A 424
ASP A 430
None
1.33A 4ryaA-1xr6A:
0.0
4ryaA-1xr6A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
3 / 3 TYR A 333
LYS A 319
LYS A 334
None
1.19A 5dbyA-1xr6A:
0.0
5dbyA-1xr6A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 5 PHE A 377
ILE A 330
GLY A 376
ILE A 221
None
0.87A 5dzkd-1xr6A:
undetectable
5dzkk-1xr6A:
undetectable
5dzky-1xr6A:
undetectable
5dzkd-1xr6A:
18.65
5dzkk-1xr6A:
18.87
5dzky-1xr6A:
0.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
5 / 11 ILE A 299
GLN A 248
PHE A 247
LEU A 250
LEU A 351
None
1.22A 5ji0A-1xr6A:
undetectable
5ji0A-1xr6A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 4 LEU A 307
MET A 231
ILE A 302
LEU A 320
None
1.21A 5nfpA-1xr6A:
undetectable
5nfpA-1xr6A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
4 / 5 PHE A  30
PRO A 406
MET A 409
VAL A  29
None
1.10A 6ekzA-1xr6A:
undetectable
6ekzA-1xr6A:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
6 / 12 LEU A 225
PRO A 222
ILE A 323
ILE A 230
VAL A 370
ILE A 330
None
1.46A 6emuA-1xr6A:
undetectable
6emuA-1xr6A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)
1xr6 GENOME POLYPROTEIN
(Rhinovirus
A)
5 / 9 ASN A  71
ILE A 302
ILE A 303
GLU A 255
ILE A 299
None
1.21A 6hloA-1xr6A:
undetectable
6hloA-1xr6A:
19.96