SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xu1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RMT_A_ADNA1501_1 (CLASS B ACID PHOSPHATASE)	1xu1	TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13 (Mus musculus)	5 / 10	ASP A 214 LEU A 156 THR A 151 GLY A 152 THR A 217	None	1.33A	1rmtA-1xu1A: undetectable	1rmtA-1xu1A: 21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_E_MK1E902_4 (POL POLYPROTEIN)	1xu1	TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13 (Mus musculus)	3 / 3	ARG A 189 VAL A 173 GLY A 237	None	0.56A	2avvE-1xu1A: undetectable	2avvE-1xu1A: 24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YA7_A_ZMRA1776_2 (NEURAMINIDASE A)	1xu1	TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13 (Mus musculus)	4 / 6	ASP A 214 ILE A 216 LEU A 156 GLU A 182	None	0.95A	2ya7A-1xu1A: undetectable	2ya7A-1xu1A: 13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YA7_B_ZMRB1776_2 (NEURAMINIDASE A)	1xu1	TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13 (Mus musculus)	4 / 6	ASP A 214 ILE A 216 LEU A 156 GLU A 182	None	0.90A	2ya7B-1xu1A: undetectable	2ya7B-1xu1A: 13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YA7_D_ZMRD1776_2 (NEURAMINIDASE A)	1xu1	TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13 (Mus musculus)	4 / 6	ASP A 214 ILE A 216 LEU A 156 GLU A 182	None	0.94A	2ya7D-1xu1A: undetectable	2ya7D-1xu1A: 13.47

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RMT_A_ADNA1501_1","CLASS B ACID PHOSPHATASE","1xu1","TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13","Mus musculus",5,"ASP A 214;LEU A 156;THR A 151;GLY A 152;THR A 217","None","1.33A","1rmtA-1xu1A:undetectable","1rmtA-1xu1A:21.10"],["2AVV_E_MK1E902_4","POL POLYPROTEIN","1xu1","TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13","Mus musculus",3,"ARG A 189;VAL A 173;GLY A 237","None","0.56A","2avvE-1xu1A:undetectable","2avvE-1xu1A:24.60"],["2YA7_A_ZMRA1776_2","NEURAMINIDASE A","1xu1","TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13","Mus musculus",4,"ASP A 214;ILE A 216;LEU A 156;GLU A 182","None","0.95A","2ya7A-1xu1A:undetectable","2ya7A-1xu1A:13.47"],["2YA7_B_ZMRB1776_2","NEURAMINIDASE A","1xu1","TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13","Mus musculus",4,"ASP A 214;ILE A 216;LEU A 156;GLU A 182","None","0.90A","2ya7B-1xu1A:undetectable","2ya7B-1xu1A:13.47"],["2YA7_D_ZMRD1776_2","NEURAMINIDASE A","1xu1","TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13","Mus musculus",4,"ASP A 214;ILE A 216;LEU A 156;GLU A 182","None","0.94A","2ya7D-1xu1A:undetectable","2ya7D-1xu1A:13.47"]]