SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xuq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		4 / 4 LEU A  90
VAL A 190
ILE A  89
TRP A  87
 None
 1.32A 1s9qB-1xuqA:
0.2		 1s9qB-1xuqA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		4 / 8 THR A 159
PRO A 160
VAL A 161
GLU A 201
 None
 1.07A 2v41G-1xuqA:
undetectable
2v41H-1xuqA:
undetectable		 2v41G-1xuqA:
18.28
2v41H-1xuqA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		4 / 8 ILE A 162
LEU A 142
PHE A 116
PHE A 113
 None
 0.93A 2vctC-1xuqA:
undetectable		 2vctC-1xuqA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		4 / 8 PRO A  98
ILE A 106
TRP A 187
ILE A 162
 None
 0.98A 3sfeB-1xuqA:
undetectable
3sfeC-1xuqA:
undetectable		 3sfeB-1xuqA:
19.92
3sfeC-1xuqA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		5 / 11 ALA A  43
HIS A  47
VAL A  65
LEU A  50
LEU A  40
 None
 1.05A 3sm2B-1xuqA:
undetectable		 3sm2B-1xuqA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		5 / 10 VAL A 190
PHE A 186
ALA A 195
ILE A 106
PHE A 116
 None
 1.30A 3t3qA-1xuqA:
undetectable		 3t3qA-1xuqA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		5 / 10 VAL A 190
PHE A 186
ALA A 195
ILE A 106
PHE A 116
 None
 1.31A 3t3qB-1xuqA:
undetectable		 3t3qB-1xuqA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		5 / 10 VAL A 190
PHE A 186
ALA A 195
ILE A 106
PHE A 116
 None
 1.31A 3t3qC-1xuqA:
undetectable		 3t3qC-1xuqA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		5 / 10 VAL A 190
PHE A 186
ALA A 195
ILE A 106
PHE A 116
 None
 1.36A 3t3qD-1xuqA:
undetectable		 3t3qD-1xuqA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_B_BQ1B1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		5 / 8 ALA A 105
ALA A 103
ILE A 106
GLU A 196
ALA A 194
 None
 1.34A 4v1fA-1xuqA:
undetectable
4v1fB-1xuqA:
undetectable		 4v1fA-1xuqA:
22.89
4v1fB-1xuqA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		5 / 12 GLY A 131
THR A  71
TYR A  36
VAL A  55
HIS A 169
 None
None
None
None
MN  A 204 (-3.3A)
 1.36A 5d0yA-1xuqA:
undetectable		 5d0yA-1xuqA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		5 / 7 TYR A 199
VAL A 161
ILE A 162
PRO A  98
ALA A 195
 None
 1.29A 5ospA-1xuqA:
undetectable		 5ospA-1xuqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1xuq SUPEROXIDE DISMUTASE
(Bacillus
anthracis) 		3 / 3 ASN A  34
VAL A  55
HIS A   4
 None
 0.83A 6a5yD-1xuqA:
undetectable		 6a5yD-1xuqA:
19.43