SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xuv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 1xuv HYPOTHETICAL PROTEIN
MM0500
(Methanosarcina
mazei) 		5 / 12 PHE A 136
PHE A 102
ILE A 154
TYR A 158
SER A 132
 None
 1.29A 1fm4A-1xuvA:
13.8		 1fm4A-1xuvA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 1xuv HYPOTHETICAL PROTEIN
MM0500
(Methanosarcina
mazei) 		3 / 3 ASP A  31
ASP A 162
LYS A 169
 None
 1.03A 1lqtB-1xuvA:
undetectable		 1lqtB-1xuvA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 1xuv HYPOTHETICAL PROTEIN
MM0500
(Methanosarcina
mazei) 		3 / 3 ASP A  31
ASP A 162
LYS A 169
 None
 1.05A 1lquB-1xuvA:
undetectable		 1lquB-1xuvA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1xuv HYPOTHETICAL PROTEIN
MM0500
(Methanosarcina
mazei) 		4 / 8 SER A 157
LEU A 130
PHE A  41
LEU A  60
 None
 0.80A 1wrlC-1xuvA:
undetectable
1wrlD-1xuvA:
undetectable		 1wrlC-1xuvA:
23.39
1wrlD-1xuvA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1xuv HYPOTHETICAL PROTEIN
MM0500
(Methanosarcina
mazei) 		3 / 3 LEU A  60
TYR A  73
GLN A  72
 None
 0.69A 2wekA-1xuvA:
undetectable		 2wekA-1xuvA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1xuv HYPOTHETICAL PROTEIN
MM0500
(Methanosarcina
mazei) 		5 / 12 ALA A 118
ASP A  43
ASP A  45
PRO A  65
PHE A  63
 None
 0.89A 3dmfA-1xuvA:
undetectable		 3dmfA-1xuvA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1xuv HYPOTHETICAL PROTEIN
MM0500
(Methanosarcina
mazei) 		4 / 8 GLN A  75
PHE A  85
ILE A  51
PHE A 102
 None
 0.84A 4fgjA-1xuvA:
undetectable
4fgjB-1xuvA:
undetectable		 4fgjA-1xuvA:
22.41
4fgjB-1xuvA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1xuv HYPOTHETICAL PROTEIN
MM0500
(Methanosarcina
mazei) 		4 / 6 GLN A  75
PHE A  85
ILE A  51
PHE A 102
 None
 0.88A 4fgkA-1xuvA:
undetectable		 4fgkA-1xuvA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H1E_A_VDXA501_1
(VITAMIN D3 RECEPTOR)		 1xuv HYPOTHETICAL PROTEIN
MM0500
(Methanosarcina
mazei) 		5 / 12 PHE A  41
LEU A 130
SER A 132
ILE A  26
SER A 157
 None
 1.22A 5h1eA-1xuvA:
undetectable		 5h1eA-1xuvA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 1xuv HYPOTHETICAL PROTEIN
MM0500
(Methanosarcina
mazei) 		4 / 6 GLY A  52
PHE A  56
TYR A  73
ILE A  74
 None
 0.78A 5kmfA-1xuvA:
undetectable
5kmfC-1xuvA:
undetectable		 5kmfA-1xuvA:
21.88
5kmfC-1xuvA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1xuv HYPOTHETICAL PROTEIN
MM0500
(Methanosarcina
mazei) 		3 / 3 SER A 132
SER A 134
PHE A  41
 None
 0.70A 5mugA-1xuvA:
undetectable		 5mugA-1xuvA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 1xuv HYPOTHETICAL PROTEIN
MM0500
(Methanosarcina
mazei) 		5 / 10 VAL A  92
ASN A  67
GLU A  64
PRO A  65
GLY A  69
 None
 1.27A 5vncC-1xuvA:
undetectable		 5vncC-1xuvA:
17.53