SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xv2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 5 GLY A 166
LEU A  11
THR A  10
VAL A 226
 None
 0.82A 1ekjF-1xv2A:
undetectable
1ekjG-1xv2A:
undetectable		 1ekjF-1xv2A:
20.48
1ekjG-1xv2A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 7 ASP A 222
GLU A 228
GLU A 229
GLU A 232
 None
 1.20A 1knyA-1xv2A:
undetectable
1knyB-1xv2A:
undetectable		 1knyA-1xv2A:
22.10
1knyB-1xv2A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 5 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.77A 1os2A-1xv2A:
undetectable		 1os2A-1xv2A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.74A 1os2D-1xv2A:
undetectable		 1os2D-1xv2A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		5 / 10 HIS A 175
GLU A  45
HIS A 186
HIS A 173
ALA A  74
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
None
 1.04A 1r55A-1xv2A:
undetectable		 1r55A-1xv2A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.76A 1uttA-1xv2A:
undetectable		 1uttA-1xv2A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 HIS A 186
GLU A 234
HIS A 173
HIS A 175
 ZN  A 801 (-3.3A)
ZN  A 801 ( 4.5A)
ZN  A 801 (-3.5A)
ZN  A 801 (-3.4A)
 1.27A 1uttA-1xv2A:
undetectable		 1uttA-1xv2A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.76A 1utzA-1xv2A:
undetectable		 1utzA-1xv2A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.72A 1utzB-1xv2A:
undetectable		 1utzB-1xv2A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		5 / 12 HIS A 173
GLY A  35
GLY A 157
LEU A   5
ILE A  76
 ZN  A 801 (-3.5A)
None
None
None
None
 1.10A 1x1aA-1xv2A:
undetectable		 1x1aA-1xv2A:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 6 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.76A 1y93A-1xv2A:
undetectable		 1y93A-1xv2A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.75A 2hu6A-1xv2A:
undetectable		 2hu6A-1xv2A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		5 / 12 HIS A 208
TYR A   6
ALA A  53
GLY A  67
TYR A  73
 None
 1.14A 2igtC-1xv2A:
undetectable		 2igtC-1xv2A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 6 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.79A 2ow9A-1xv2A:
undetectable		 2ow9A-1xv2A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.81A 2ow9B-1xv2A:
undetectable		 2ow9B-1xv2A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.76A 2ozrC-1xv2A:
undetectable		 2ozrC-1xv2A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.81A 2ozrD-1xv2A:
undetectable		 2ozrD-1xv2A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.79A 2ozrE-1xv2A:
undetectable		 2ozrE-1xv2A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 5 GLN A 200
PHE A 202
PHE A 158
GLY A  32
 None
 1.38A 2qmzA-1xv2A:
undetectable
2qmzB-1xv2A:
undetectable		 2qmzA-1xv2A:
24.62
2qmzB-1xv2A:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 5 GLN A 207
PHE A 205
PHE A 109
GLY A 166
 None
 1.25A 2qmzA-1xv2A:
undetectable
2qmzB-1xv2A:
undetectable		 2qmzA-1xv2A:
24.62
2qmzB-1xv2A:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		5 / 12 TYR A  54
VAL A 156
GLY A 157
ILE A  76
ILE A  25
 None
 1.14A 3ijdB-1xv2A:
undetectable		 3ijdB-1xv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 5 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.78A 3kecA-1xv2A:
undetectable		 3kecA-1xv2A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 5 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.74A 3likA-1xv2A:
undetectable		 3likA-1xv2A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.74A 3lilA-1xv2A:
undetectable		 3lilA-1xv2A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 5 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.71A 3ljgA-1xv2A:
undetectable		 3ljgA-1xv2A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 5 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.76A 3lkaA-1xv2A:
undetectable		 3lkaA-1xv2A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		5 / 12 LEU A   5
ALA A  74
GLY A   9
ALA A  23
HIS A  31
 None
 0.98A 3ou6B-1xv2A:
undetectable		 3ou6B-1xv2A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		5 / 12 LEU A   5
ALA A  74
GLY A   9
ALA A  23
HIS A  31
 None
 1.00A 3ou7B-1xv2A:
undetectable		 3ou7B-1xv2A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 7 HIS A 175
GLY A 184
ALA A  56
PHE A  62
 ZN  A 801 (-3.4A)
None
None
None
 0.86A 3tehB-1xv2A:
undetectable		 3tehB-1xv2A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 6 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.86A 4a7bA-1xv2A:
undetectable		 4a7bA-1xv2A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		5 / 11 PHE A 172
VAL A 112
ILE A 114
PHE A 190
MET A 103
 None
 1.33A 4dz2A-1xv2A:
undetectable
4dz2B-1xv2A:
undetectable		 4dz2A-1xv2A:
19.83
4dz2B-1xv2A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		5 / 11 MET A 103
PHE A 172
VAL A 112
ILE A 114
PHE A 190
 None
 1.35A 4dz2A-1xv2A:
undetectable
4dz2B-1xv2A:
undetectable		 4dz2A-1xv2A:
19.83
4dz2B-1xv2A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 VAL A 156
ALA A 111
ILE A  76
THR A  77
 None
 0.94A 5e4dB-1xv2A:
undetectable		 5e4dB-1xv2A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 4 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.74A 5n5jA-1xv2A:
undetectable		 5n5jA-1xv2A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 5 HIS A 175
GLU A  45
HIS A 186
HIS A 173
 ZN  A 801 (-3.4A)
ZN  A 801 ( 4.4A)
ZN  A 801 (-3.3A)
ZN  A 801 (-3.5A)
 0.75A 5n5kA-1xv2A:
undetectable		 5n5kA-1xv2A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		3 / 3 LYS A 147
HIS A 120
HIS A 122
 None
 1.22A 5oexA-1xv2A:
undetectable		 5oexA-1xv2A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		3 / 3 LYS A 147
HIS A 120
HIS A 122
 None
 1.20A 5oexB-1xv2A:
undetectable		 5oexB-1xv2A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		3 / 3 LYS A 147
HIS A 120
HIS A 122
 None
 1.22A 5oexC-1xv2A:
undetectable		 5oexC-1xv2A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		3 / 3 LYS A 147
HIS A 120
HIS A 122
 None
 1.23A 5oexD-1xv2A:
undetectable		 5oexD-1xv2A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6L_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		5 / 9 ILE A 230
ALA A 233
MET A 126
LEU A  14
ILE A  36
 None
 1.32A 5z6lA-1xv2A:
undetectable		 5z6lA-1xv2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE
(Staphylococcus
aureus) 		4 / 7 PHE A  48
LEU A  29
GLY A  67
GLY A  21
 None
 0.76A 6eu9D-1xv2A:
undetectable		 6eu9D-1xv2A:
18.31