SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xw8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 8 ALA A 244
ASP A   4
ILE A 135
GLY A  55
ILE A  54
 None
 1.18A 1sh9A-1xw8A:
undetectable		 1sh9A-1xw8A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 8 MET A 194
LEU A 192
LEU A   5
VAL A 215
 None
 0.96A 2bdmA-1xw8A:
undetectable		 2bdmA-1xw8A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 8 LEU A   5
PHE A 235
LEU A 231
PHE A 227
 None
 0.88A 2eilP-1xw8A:
undetectable
2eilW-1xw8A:
undetectable		 2eilP-1xw8A:
18.97
2eilW-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 8 LEU A 188
GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 1.27A 2eilP-1xw8A:
undetectable
2eilW-1xw8A:
undetectable		 2eilP-1xw8A:
18.97
2eilW-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 GLU A 143
ASP A 121
TYR A 151
 None
 0.81A 2yvlB-1xw8A:
undetectable		 2yvlB-1xw8A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 6 LEU A   5
PHE A 235
LEU A 231
PHE A 227
 None
 0.93A 3abkP-1xw8A:
undetectable
3abkW-1xw8A:
undetectable		 3abkP-1xw8A:
18.97
3abkW-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 8 LEU A   5
PHE A 235
LEU A 231
PHE A 227
 None
 0.95A 3asoC-1xw8A:
undetectable
3asoJ-1xw8A:
undetectable		 3asoC-1xw8A:
18.97
3asoJ-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 8 LEU A 188
GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 1.25A 3asoC-1xw8A:
undetectable
3asoJ-1xw8A:
undetectable		 3asoC-1xw8A:
18.97
3asoJ-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_D_TMQD614_1
(DHFR-TS)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 10 VAL A  52
ALA A 244
ILE A 135
ASP A   4
PRO A 105
 None
 1.23A 3clbD-1xw8A:
undetectable		 3clbD-1xw8A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 GLY A 148
GLY A 152
GLU A 143
ALA A 124
 None
 0.84A 3fpjB-1xw8A:
undetectable		 3fpjB-1xw8A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_D_TMQD614_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 10 VAL A  52
ALA A 244
ILE A 135
ASP A   4
PRO A 105
 None
 1.24A 3hbbD-1xw8A:
undetectable		 3hbbD-1xw8A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 6 LEU A   5
PHE A 235
LEU A 231
PHE A 227
 None
 0.92A 3wg7P-1xw8A:
undetectable
3wg7W-1xw8A:
undetectable		 3wg7P-1xw8A:
18.97
3wg7W-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 7 LEU A  22
ALA A   7
VAL A  52
ILE A  39
THR A  21
 None
 1.27A 4eyrA-1xw8A:
undetectable		 4eyrA-1xw8A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 12 ILE A 135
LEU A 153
GLY A 148
VAL A 127
ALA A 126
 None
 1.22A 4foxD-1xw8A:
undetectable		 4foxD-1xw8A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 12 ILE A 135
LEU A 153
GLY A 148
VAL A 127
ALA A 126
 None
 1.24A 4fqsA-1xw8A:
0.0		 4fqsA-1xw8A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 12 HIS A 106
ALA A  56
ASP A  16
GLY A  10
GLY A  12
 None
 1.18A 4hfpB-1xw8A:
undetectable		 4hfpB-1xw8A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 6 ARG A 174
ASP A 162
VAL A 210
ALA A 212
 None
 0.95A 4nkxA-1xw8A:
undetectable		 4nkxA-1xw8A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 12 ALA A 126
ALA A  56
ALA A  88
GLY A  87
LEU A  89
 None
 1.06A 4oaeA-1xw8A:
undetectable		 4oaeA-1xw8A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 9 ALA A  93
VAL A 127
GLY A  87
ILE A  54
VAL A 103
 None
 1.07A 4r21B-1xw8A:
undetectable		 4r21B-1xw8A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 6 LEU A 136
LYS A 104
PRO A 105
GLU A 158
 None
 1.25A 4z4gA-1xw8A:
2.4		 4z4gA-1xw8A:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 LEU A   5
PHE A 235
LEU A 231
PHE A 227
 None
 0.93A 5b1aC-1xw8A:
undetectable
5b1aJ-1xw8A:
undetectable		 5b1aC-1xw8A:
18.97
5b1aJ-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 7 LEU A 188
GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 1.13A 5b1aC-1xw8A:
undetectable
5b1aJ-1xw8A:
undetectable		 5b1aC-1xw8A:
18.97
5b1aJ-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 LEU A   5
PHE A 235
LEU A 231
PHE A 227
 None
 0.89A 5b1aP-1xw8A:
undetectable
5b1aW-1xw8A:
undetectable		 5b1aP-1xw8A:
18.97
5b1aW-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 7 LEU A 188
GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 1.12A 5b1aP-1xw8A:
undetectable
5b1aW-1xw8A:
undetectable		 5b1aP-1xw8A:
18.97
5b1aW-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 LEU A   5
PHE A 235
LEU A 231
PHE A 227
 None
 0.96A 5b3sC-1xw8A:
undetectable
5b3sJ-1xw8A:
undetectable		 5b3sC-1xw8A:
18.97
5b3sJ-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 7 LEU A 188
GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 1.26A 5b3sC-1xw8A:
undetectable
5b3sJ-1xw8A:
undetectable		 5b3sC-1xw8A:
18.97
5b3sJ-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 12 HIS A 197
GLY A 198
ALA A 161
ILE A 240
MET A   1
 None
 1.09A 5igyA-1xw8A:
undetectable		 5igyA-1xw8A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 LEU A   5
PHE A 235
LEU A 231
PHE A 227
 None
 0.93A 5iy5C-1xw8A:
undetectable
5iy5J-1xw8A:
undetectable		 5iy5C-1xw8A:
19.79
5iy5J-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 7 LEU A 188
GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 1.13A 5iy5C-1xw8A:
undetectable
5iy5J-1xw8A:
undetectable		 5iy5C-1xw8A:
19.79
5iy5J-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 5 VAL A  23
ASN A  27
ASP A   8
LEU A   9
 None
 1.20A 5m0iB-1xw8A:
undetectable		 5m0iB-1xw8A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.70A 5qglA-1xw8A:
undetectable		 5qglA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.67A 5qguA-1xw8A:
undetectable		 5qguA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.62A 5qgvA-1xw8A:
undetectable		 5qgvA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.61A 5qgwA-1xw8A:
undetectable		 5qgwA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.62A 5qgxA-1xw8A:
undetectable		 5qgxA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.62A 5qgyA-1xw8A:
undetectable		 5qgyA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.62A 5qgzA-1xw8A:
undetectable		 5qgzA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.63A 5qh0A-1xw8A:
undetectable		 5qh0A-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.61A 5qh1A-1xw8A:
undetectable		 5qh1A-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.60A 5qh2A-1xw8A:
undetectable		 5qh2A-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.62A 5qh3A-1xw8A:
undetectable		 5qh3A-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.66A 5qh4A-1xw8A:
undetectable		 5qh4A-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.65A 5qh5A-1xw8A:
undetectable		 5qh5A-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.63A 5qh6A-1xw8A:
undetectable		 5qh6A-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.65A 5qh7A-1xw8A:
undetectable		 5qh7A-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.66A 5qh9A-1xw8A:
undetectable		 5qh9A-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.63A 5qhaA-1xw8A:
undetectable		 5qhaA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.67A 5qhcA-1xw8A:
undetectable		 5qhcA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.65A 5qheA-1xw8A:
undetectable		 5qheA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.63A 5qhfA-1xw8A:
undetectable		 5qhfA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.68A 5qhgA-1xw8A:
undetectable		 5qhgA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		3 / 3 VAL A 215
VAL A 159
GLN A 190
 None
 0.65A 5qhhA-1xw8A:
undetectable		 5qhhA-1xw8A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 12 ALA A 211
LEU A 139
VAL A 200
ASP A 162
THR A 191
 None
 1.49A 5vlmD-1xw8A:
0.3		 5vlmD-1xw8A:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 8 GLN A  85
GLY A  31
ILE A  28
GLN A  96
 None
 1.02A 5vlmD-1xw8A:
undetectable		 5vlmD-1xw8A:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 5 LEU A   5
PHE A 235
LEU A 231
PHE A 227
 None
 0.87A 5x19C-1xw8A:
undetectable
5x19J-1xw8A:
undetectable		 5x19C-1xw8A:
18.97
5x19J-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 5 LEU A 188
PHE A 227
LEU A 231
PHE A 235
 None
 1.04A 5x19C-1xw8A:
undetectable
5x19J-1xw8A:
undetectable		 5x19C-1xw8A:
18.97
5x19J-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 LEU A   5
PHE A 235
LEU A 231
PHE A 227
 None
 0.92A 5z84C-1xw8A:
undetectable
5z84J-1xw8A:
undetectable		 5z84C-1xw8A:
18.97
5z84J-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 7 LEU A 188
GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 1.03A 5z84C-1xw8A:
undetectable
5z84J-1xw8A:
undetectable		 5z84C-1xw8A:
18.97
5z84J-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 6 GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 0.86A 5z84P-1xw8A:
undetectable
5z84W-1xw8A:
undetectable		 5z84P-1xw8A:
18.97
5z84W-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 0.85A 5z85C-1xw8A:
undetectable
5z85J-1xw8A:
undetectable		 5z85C-1xw8A:
18.97
5z85J-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 LEU A 188
GLN A 186
PHE A 227
PHE A 235
 None
 0.89A 5z85C-1xw8A:
undetectable
5z85J-1xw8A:
undetectable		 5z85C-1xw8A:
18.97
5z85J-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 6 GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 0.92A 5z85P-1xw8A:
0.0
5z85W-1xw8A:
undetectable		 5z85P-1xw8A:
18.97
5z85W-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 6 GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 0.86A 5z86C-1xw8A:
0.0
5z86J-1xw8A:
undetectable		 5z86C-1xw8A:
18.97
5z86J-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 6 GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 0.84A 5z86P-1xw8A:
0.0
5z86W-1xw8A:
undetectable		 5z86P-1xw8A:
18.97
5z86W-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 0.77A 5zcoC-1xw8A:
undetectable
5zcoJ-1xw8A:
undetectable		 5zcoC-1xw8A:
18.97
5zcoJ-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 LEU A 188
GLN A 186
PHE A 227
PHE A 235
 None
 0.87A 5zcoC-1xw8A:
undetectable
5zcoJ-1xw8A:
undetectable		 5zcoC-1xw8A:
18.97
5zcoJ-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 6 GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 0.83A 5zcoP-1xw8A:
0.0
5zcoW-1xw8A:
undetectable		 5zcoP-1xw8A:
18.97
5zcoW-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 6 GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 0.82A 5zcpC-1xw8A:
undetectable
5zcpJ-1xw8A:
undetectable		 5zcpC-1xw8A:
18.97
5zcpJ-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 6 GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 0.87A 5zcpP-1xw8A:
0.0
5zcpW-1xw8A:
undetectable		 5zcpP-1xw8A:
18.97
5zcpW-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 0.88A 5zcqC-1xw8A:
undetectable
5zcqJ-1xw8A:
undetectable		 5zcqC-1xw8A:
18.97
5zcqJ-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 LEU A 188
GLN A 186
PHE A 227
PHE A 235
 None
 0.94A 5zcqC-1xw8A:
undetectable
5zcqJ-1xw8A:
undetectable		 5zcqC-1xw8A:
18.97
5zcqJ-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 GLN A 186
PHE A 227
LEU A 231
PHE A 235
 None
 0.86A 5zcqP-1xw8A:
undetectable
5zcqW-1xw8A:
undetectable		 5zcqP-1xw8A:
18.97
5zcqW-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		4 / 7 LEU A 188
GLN A 186
PHE A 227
PHE A 235
 None
 0.90A 5zcqP-1xw8A:
undetectable
5zcqW-1xw8A:
undetectable		 5zcqP-1xw8A:
18.97
5zcqW-1xw8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FZB_B_SRYB301_1
(STREPTOMYCIN
3''-ADENYLYLTRANSFER
ASE)		 1xw8 UPF0271 PROTEIN YBGL
(Escherichia
coli) 		5 / 12 GLU A 158
ASP A   8
LEU A  20
HIS A 102
ILE A  54
 None
 1.43A 6fzbB-1xw8A:
0.3		 6fzbB-1xw8A:
15.84