SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xwv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1xwv DER F II
(Dermatophagoides
farinae) 		6 / 12 ILE A  29
LEU A  37
VAL A  65
ALA A  56
ILE A  54
ILE A  52
 None
PE3  A1001 (-4.5A)
PE3  A1001 ( 4.0A)
PE3  A1001 ( 4.1A)
PE3  A1001 (-4.8A)
PE3  A1001 ( 4.3A)
 1.09A 1epbA-1xwvA:
undetectable		 1epbA-1xwvA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1xwv DER F II
(Dermatophagoides
farinae) 		6 / 12 ILE A  29
LEU A  37
VAL A  65
ALA A  56
ILE A  54
ILE A  52
 None
PE3  A1001 (-4.5A)
PE3  A1001 ( 4.0A)
PE3  A1001 ( 4.1A)
PE3  A1001 (-4.8A)
PE3  A1001 ( 4.3A)
 1.12A 1epbB-1xwvA:
undetectable		 1epbB-1xwvA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A2000_1
(P38A)		 1xwv DER F II
(Dermatophagoides
farinae) 		5 / 12 ILE A  52
VAL A 104
ILE A 127
ILE A  68
TYR A  90
 PE3  A1001 ( 4.3A)
None
None
None
PE3  A1001 (-4.4A)
 1.23A 3ohtA-1xwvA:
undetectable
3ohtB-1xwvA:
undetectable		 3ohtA-1xwvA:
15.58
3ohtB-1xwvA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1xwv DER F II
(Dermatophagoides
farinae) 		3 / 3 ARG A 128
ASP A 129
ARG A  31
 None
 0.58A 4wq4B-1xwvA:
undetectable		 4wq4B-1xwvA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 1xwv DER F II
(Dermatophagoides
farinae) 		4 / 8 ILE A 127
ALA A  98
ALA A  56
ILE A  63
 None
PE3  A1001 ( 3.7A)
PE3  A1001 ( 4.1A)
None
 0.65A 5mvmA-1xwvA:
undetectable
5mvmB-1xwvA:
undetectable		 5mvmA-1xwvA:
23.26
5mvmB-1xwvA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1xwv DER F II
(Dermatophagoides
farinae) 		4 / 7 VAL A  65
ILE A  63
VAL A 106
ALA A  56
 PE3  A1001 ( 4.0A)
None
PE3  A1001 ( 4.7A)
PE3  A1001 ( 4.1A)
 0.65A 5ospA-1xwvA:
undetectable		 5ospA-1xwvA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1xwv DER F II
(Dermatophagoides
farinae) 		4 / 7 VAL A  65
ILE A  63
VAL A 106
ALA A  56
 PE3  A1001 ( 4.0A)
None
PE3  A1001 ( 4.7A)
PE3  A1001 ( 4.1A)
 0.66A 5osrA-1xwvA:
undetectable		 5osrA-1xwvA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 1xwv DER F II
(Dermatophagoides
farinae) 		5 / 10 ILE A  68
ILE A  13
ALA A 118
LEU A 110
ALA A  50
 None
None
PE3  A1001 ( 4.7A)
PE3  A1001 ( 4.0A)
None
 1.37A 5zjiB-1xwvA:
undetectable		 5zjiB-1xwvA:
17.39