SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xx5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1xx5 NATRIN 1
(Naja
atra) 		3 / 3 ARG A  51
VAL A 144
TRP A  52
 None
 1.20A 1qw6A-1xx5A:
undetectable		 1qw6A-1xx5A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1xx5 NATRIN 1
(Naja
atra) 		3 / 3 ARG A  51
VAL A 144
TRP A  52
 None
 1.15A 1qwcA-1xx5A:
undetectable		 1qwcA-1xx5A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1xx5 NATRIN 1
(Naja
atra) 		3 / 3 ARG A  51
VAL A 144
TRP A  52
 None
 1.18A 1vagA-1xx5A:
undetectable		 1vagA-1xx5A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1xx5 NATRIN 1
(Naja
atra) 		3 / 3 ARG A  51
VAL A 144
TRP A  52
 None
 1.22A 1zviA-1xx5A:
undetectable		 1zviA-1xx5A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1xx5 NATRIN 1
(Naja
atra) 		4 / 7 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 0.97A 3ag4N-1xx5A:
undetectable
3ag4W-1xx5A:
undetectable		 3ag4N-1xx5A:
16.47
3ag4W-1xx5A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xx5 NATRIN 1
(Naja
atra) 		4 / 6 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 1.04A 3wg7A-1xx5A:
undetectable
3wg7J-1xx5A:
undetectable		 3wg7A-1xx5A:
16.47
3wg7J-1xx5A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 1xx5 NATRIN 1
(Naja
atra) 		4 / 7 ASN A  48
GLN A 146
VAL A 144
GLU A  75
 None
 0.81A 4mv7A-1xx5A:
undetectable		 4mv7A-1xx5A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 1xx5 NATRIN 1
(Naja
atra) 		4 / 7 GLY A 114
TYR A 147
ASN A 152
HIS A 115
 EOH  A 501 ( 3.7A)
None
None
EOH  A 501 ( 4.0A)
 1.18A 4ws0A-1xx5A:
undetectable		 4ws0A-1xx5A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xx5 NATRIN 1
(Naja
atra) 		4 / 6 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 1.07A 5b1aN-1xx5A:
undetectable
5b1aW-1xx5A:
undetectable		 5b1aN-1xx5A:
16.47
5b1aW-1xx5A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1xx5 NATRIN 1
(Naja
atra) 		3 / 3 ARG A  51
VAL A 144
TRP A  52
 None
 1.14A 5fvoA-1xx5A:
undetectable		 5fvoA-1xx5A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xx5 NATRIN 1
(Naja
atra) 		4 / 6 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 1.02A 6nmfN-1xx5A:
undetectable
6nmfW-1xx5A:
undetectable		 6nmfN-1xx5A:
16.47
6nmfW-1xx5A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1xx5 NATRIN 1
(Naja
atra) 		4 / 7 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 0.97A 6nmpA-1xx5A:
undetectable
6nmpJ-1xx5A:
undetectable		 6nmpA-1xx5A:
16.47
6nmpJ-1xx5A:
14.75