SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xxb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 1xxb ARGININE REPRESSOR
(Escherichia
coli) 		4 / 7 THR A 100
ILE A 108
LEU A 112
PHE A 152
 None
 0.89A 4ejjD-1xxbA:
undetectable		 4ejjD-1xxbA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 1xxb ARGININE REPRESSOR
(Escherichia
coli) 		5 / 12 ILE A  89
LEU A 151
THR A 124
ILE A 121
LEU A 144
 None
 1.16A 5e8qB-1xxbA:
undetectable		 5e8qB-1xxbA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1xxb ARGININE REPRESSOR
(Escherichia
coli) 		3 / 3 LYS A  83
LEU A 112
ILE A  89
 None
 0.79A 5kc4A-1xxbA:
undetectable		 5kc4A-1xxbA:
21.48