SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xxg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 1xxg ENTEROTOXIN
(Staphylococcus
aureus) 		3 / 3 LEU A  50
SER A  47
ASN A  68
 None
 0.66A 1bx4A-1xxgA:
undetectable		 1bx4A-1xxgA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 1xxg ENTEROTOXIN
(Staphylococcus
aureus) 		5 / 11 PRO A 206
LEU A  28
TYR A  87
GLY A  84
TYR A  29
 None
 1.33A 1fkpA-1xxgA:
undetectable		 1fkpA-1xxgA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1xxg ENTEROTOXIN
(Staphylococcus
aureus) 		5 / 11 PRO A 206
LEU A  28
TYR A  87
GLY A  84
TYR A  29
 None
 1.30A 1lwcA-1xxgA:
undetectable		 1lwcA-1xxgA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 1xxg ENTEROTOXIN
(Staphylococcus
aureus) 		4 / 7 LEU A  28
TYR A 110
GLY A  84
TYR A  29
 None
 0.99A 1lweA-1xxgA:
undetectable		 1lweA-1xxgA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 1xxg ENTEROTOXIN
(Staphylococcus
aureus) 		4 / 6 ILE A 151
PHE A 191
ILE A 224
GLU A 185
 None
 1.26A 4zzcA-1xxgA:
undetectable
4zzcB-1xxgA:
undetectable		 4zzcA-1xxgA:
23.22
4zzcB-1xxgA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 1xxg ENTEROTOXIN
(Staphylococcus
aureus) 		4 / 6 ILE A 151
PHE A 191
ILE A 224
GLU A 185
 None
 1.29A 4zzcB-1xxgA:
undetectable
4zzcC-1xxgA:
undetectable		 4zzcB-1xxgA:
23.22
4zzcC-1xxgA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1xxg ENTEROTOXIN
(Staphylococcus
aureus) 		5 / 11 PRO A 206
LEU A  28
TYR A  87
GLY A  84
TYR A  29
 None
 1.33A 5hbmA-1xxgA:
undetectable		 5hbmA-1xxgA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1xxg ENTEROTOXIN
(Staphylococcus
aureus) 		4 / 6 PHE A 140
VAL A 128
ILE A 181
ASP A 155
 None
 1.25A 5iwuA-1xxgA:
undetectable		 5iwuA-1xxgA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 1xxg ENTEROTOXIN
(Staphylococcus
aureus) 		4 / 8 ILE A 132
VAL A 228
LEU A 162
THR A 163
 None
 0.60A 5og9A-1xxgA:
undetectable		 5og9A-1xxgA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1xxg ENTEROTOXIN
(Staphylococcus
aureus) 		3 / 3 ASP A 194
PHE A 209
ARG A 159
 None
 1.06A 5yw0A-1xxgA:
undetectable		 5yw0A-1xxgA:
21.82