SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xxr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 1xxr MANNOSE-BINDING
LECTIN
(Morus
nigra) 		3 / 3 ALA A  51
VAL A 152
TRP A  30
 None
 0.87A 1nt6A-1xxrA:
undetectable		 1nt6A-1xxrA:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 1xxr MANNOSE-BINDING
LECTIN
(Morus
nigra) 		3 / 3 ALA A  51
VAL A 152
TRP A  30
 None
 0.87A 1nt6B-1xxrA:
undetectable		 1nt6B-1xxrA:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 1xxr MANNOSE-BINDING
LECTIN
(Morus
nigra) 		4 / 7 THR A  16
VAL A 142
VAL A  19
ILE A  17
 None
 0.84A 1p7rA-1xxrA:
undetectable		 1p7rA-1xxrA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 1xxr MANNOSE-BINDING
LECTIN
(Morus
nigra) 		4 / 7 ASP A  32
PHE A 144
GLY A 156
PHE A  52
 None
 1.01A 3vnsA-1xxrA:
undetectable		 3vnsA-1xxrA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 1xxr MANNOSE-BINDING
LECTIN
(Morus
nigra) 		4 / 8 LEU A  89
ILE A 141
GLY A 156
ILE A 155
 None
 0.91A 3wxoA-1xxrA:
undetectable		 3wxoA-1xxrA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 1xxr MANNOSE-BINDING
LECTIN
(Morus
nigra) 		4 / 5 SER A  34
GLY A  33
THR A  13
ASP A  31
 None
 1.14A 4eohA-1xxrA:
undetectable		 4eohA-1xxrA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1xxr MANNOSE-BINDING
LECTIN
(Morus
nigra) 		4 / 7 ASN A  86
PRO A  85
PHE A  84
TYR A 121
 None
 1.41A 5amkB-1xxrA:
0.0		 5amkB-1xxrA:
22.41