SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xyn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 1xyn ENDO-1,4-BETA-XYLANA
SE I
(Trichoderma
reesei) 		4 / 4 VAL A  26
ALA A 172
LEU A  63
PHE A  54
 None
 1.26A 1q97B-1xynA:
undetectable		 1q97B-1xynA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 1xyn ENDO-1,4-BETA-XYLANA
SE I
(Trichoderma
reesei) 		3 / 3 TRP A 146
GLN A 140
TRP A  68
 None
 1.32A 2vqyA-1xynA:
undetectable		 2vqyA-1xynA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1xyn ENDO-1,4-BETA-XYLANA
SE I
(Trichoderma
reesei) 		3 / 3 SER A 175
GLN A 174
PHE A  50
 None
 0.40A 3g4lC-1xynA:
undetectable		 3g4lC-1xynA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 1xyn ENDO-1,4-BETA-XYLANA
SE I
(Trichoderma
reesei) 		4 / 5 ASP A   6
VAL A  38
GLY A  37
TYR A   5
 None
 1.39A 3w9tA-1xynA:
undetectable		 3w9tA-1xynA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 1xyn ENDO-1,4-BETA-XYLANA
SE I
(Trichoderma
reesei) 		4 / 5 ASP A   6
VAL A  38
GLY A  37
TYR A   5
 None
 1.39A 3w9tB-1xynA:
undetectable		 3w9tB-1xynA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 1xyn ENDO-1,4-BETA-XYLANA
SE I
(Trichoderma
reesei) 		4 / 5 ASP A   6
VAL A  38
GLY A  37
TYR A   5
 None
 1.39A 3w9tC-1xynA:
undetectable		 3w9tC-1xynA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 1xyn ENDO-1,4-BETA-XYLANA
SE I
(Trichoderma
reesei) 		4 / 5 ASP A   6
VAL A  38
GLY A  37
TYR A   5
 None
 1.39A 3w9tD-1xynA:
undetectable		 3w9tD-1xynA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 1xyn ENDO-1,4-BETA-XYLANA
SE I
(Trichoderma
reesei) 		4 / 5 ASP A   6
VAL A  38
GLY A  37
TYR A   5
 None
 1.39A 3w9tE-1xynA:
undetectable		 3w9tE-1xynA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 1xyn ENDO-1,4-BETA-XYLANA
SE I
(Trichoderma
reesei) 		4 / 5 ASP A   6
VAL A  38
GLY A  37
TYR A   5
 None
 1.38A 3w9tF-1xynA:
undetectable		 3w9tF-1xynA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 1xyn ENDO-1,4-BETA-XYLANA
SE I
(Trichoderma
reesei) 		4 / 5 ASP A   6
VAL A  38
GLY A  37
TYR A   5
 None
 1.39A 3w9tG-1xynA:
undetectable		 3w9tG-1xynA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1xyn ENDO-1,4-BETA-XYLANA
SE I
(Trichoderma
reesei) 		3 / 3 TYR A 102
PHE A  50
ARG A 128
 None
 1.00A 4g19D-1xynA:
undetectable		 4g19D-1xynA:
20.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1xyn ENDO-1,4-BETA-XYLANA
SE I
(Trichoderma
reesei) 		5 / 12 VAL A  35
TRP A  68
TYR A  77
PRO A 113
TYR A 158
 None
 0.84A 5tzoA-1xynA:
28.4		 5tzoA-1xynA:
43.16