SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xz9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1xz9 AFADIN
(Homo
sapiens) 		4 / 8 SER A  44
SER A  26
ILE A  27
GLY A  49
 None
 1.00A 1meiA-1xz9A:
undetectable		 1meiA-1xz9A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 1xz9 AFADIN
(Homo
sapiens) 		4 / 7 ILE A  40
PRO A  10
ILE A  13
LEU A  57
 None
 0.88A 2q83A-1xz9A:
undetectable		 2q83A-1xz9A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)		 1xz9 AFADIN
(Homo
sapiens) 		4 / 5 PRO A  10
ILE A  13
ARG A  56
ASP A  61
 None
 1.16A 2rhmD-1xz9A:
undetectable		 2rhmD-1xz9A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 1xz9 AFADIN
(Homo
sapiens) 		5 / 9 ASP A  61
LEU A  17
ALA A  50
VAL A  53
ASP A  52
 None
 1.33A 6c2mB-1xz9A:
undetectable		 6c2mB-1xz9A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1xz9 AFADIN
(Homo
sapiens) 		3 / 3 LYS A  47
SER A  26
SER A  44
 None
 0.90A 6gbfA-1xz9A:
undetectable		 6gbfA-1xz9A:
13.64