SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1xzo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 1xzo HYPOTHETICAL PROTEIN
YPMQ
(Bacillus
subtilis) 		4 / 7 PHE A  75
PHE A  16
PHE A 115
VAL A 142
 None
 1.00A 1lh6A-1xzoA:
undetectable		 1lh6A-1xzoA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1xzo HYPOTHETICAL PROTEIN
YPMQ
(Bacillus
subtilis) 		3 / 3 ASP A 151
ASP A 166
ASN A 153
 None
CD  A1004 (-2.2A)
None
 0.74A 2bm9D-1xzoA:
undetectable		 2bm9D-1xzoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR202_1
(PROTEIN S100-A4)		 1xzo HYPOTHETICAL PROTEIN
YPMQ
(Bacillus
subtilis) 		5 / 11 CYH A  49
ASP A  39
SER A  74
PHE A  90
PHE A 103
 None
 1.43A 3ko0Q-1xzoA:
undetectable
3ko0R-1xzoA:
undetectable
3ko0S-1xzoA:
undetectable
3ko0T-1xzoA:
undetectable		 3ko0Q-1xzoA:
19.43
3ko0R-1xzoA:
19.43
3ko0S-1xzoA:
19.43
3ko0T-1xzoA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 1xzo HYPOTHETICAL PROTEIN
YPMQ
(Bacillus
subtilis) 		5 / 12 PHE A 120
LEU A  31
LEU A  28
PHE A  75
LEU A 104
 None
None
CA  A1016 ( 4.5A)
None
None
 1.31A 5uanB-1xzoA:
undetectable		 5uanB-1xzoA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 1xzo HYPOTHETICAL PROTEIN
YPMQ
(Bacillus
subtilis) 		5 / 9 VAL A 167
ALA A 170
SER A 171
VAL A  70
GLY A 143
 None
 1.26A 6bklA-1xzoA:
undetectable
6bklB-1xzoA:
undetectable
6bklC-1xzoA:
undetectable
6bklD-1xzoA:
undetectable		 6bklA-1xzoA:
9.20
6bklB-1xzoA:
9.20
6bklC-1xzoA:
9.20
6bklD-1xzoA:
9.20