SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y0k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 1y0k HYPOTHETICAL PROTEIN
PA4535
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 192
ALA A  65
PHE A  67
PHE A  62
 None
 1.28A 1lqtA-1y0kA:
undetectable		 1lqtA-1y0kA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 1y0k HYPOTHETICAL PROTEIN
PA4535
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 192
ALA A  65
PHE A  67
PHE A  62
 None
 1.29A 1lquA-1y0kA:
undetectable		 1lquA-1y0kA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L7K_A_EDTA739_0
(TEICHOIC ACID
BIOSYNTHESIS PROTEIN
F)		 1y0k HYPOTHETICAL PROTEIN
PA4535
(Pseudomonas
aeruginosa) 		4 / 5 LEU A   7
ARG A   8
ARG A 149
LYS A 105
 None
 1.33A 3l7kA-1y0kA:
0.0
3l7kB-1y0kA:
0.0		 3l7kA-1y0kA:
14.92
3l7kB-1y0kA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 1y0k HYPOTHETICAL PROTEIN
PA4535
(Pseudomonas
aeruginosa) 		3 / 3 PHE A  67
SER A 171
SER A 173
 None
 0.86A 3ufgB-1y0kA:
undetectable		 3ufgB-1y0kA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 1y0k HYPOTHETICAL PROTEIN
PA4535
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  36
TYR A  45
GLU A  39
 None
 0.71A 4zzbE-1y0kA:
undetectable		 4zzbE-1y0kA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1y0k HYPOTHETICAL PROTEIN
PA4535
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 118
ALA A 119
LEU A 172
 None
 0.53A 5uunB-1y0kA:
undetectable		 5uunB-1y0kA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1y0k HYPOTHETICAL PROTEIN
PA4535
(Pseudomonas
aeruginosa) 		5 / 12 PHE A  70
LEU A 147
LEU A 122
LEU A 183
TYR A 164
 None
 1.38A 5y2oA-1y0kA:
undetectable		 5y2oA-1y0kA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1y0k HYPOTHETICAL PROTEIN
PA4535
(Pseudomonas
aeruginosa) 		5 / 12 PHE A  70
LEU A 147
LEU A 122
LEU A 183
TYR A 164
 None
 1.34A 5ycpA-1y0kA:
undetectable		 5ycpA-1y0kA:
17.00