SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1y11 HYPOTHETICAL PROTEIN
RV1264/MT1302
(Mycobacterium
tuberculosis) 		3 / 3 THR A 280
LEU A 284
VAL A 287
 None
 0.15A 1mz9E-1y11A:
undetectable		 1mz9E-1y11A:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1y11 HYPOTHETICAL PROTEIN
RV1264/MT1302
(Mycobacterium
tuberculosis) 		4 / 6 GLY A 304
VAL A 320
ALA A 302
SER A 338
 None
 0.96A 1p6kA-1y11A:
undetectable		 1p6kA-1y11A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 1y11 HYPOTHETICAL PROTEIN
RV1264/MT1302
(Mycobacterium
tuberculosis) 		5 / 8 ARG A 373
LEU A 334
VAL A 369
VAL A 339
VAL A 374
 GOL  A 410 ( 4.4A)
None
None
None
None
 1.47A 2bdmA-1y11A:
1.1		 2bdmA-1y11A:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 1y11 HYPOTHETICAL PROTEIN
RV1264/MT1302
(Mycobacterium
tuberculosis) 		5 / 9 THR A 217
LEU A 277
VAL A 281
VAL A 374
VAL A 333
 None
 1.38A 2l8mA-1y11A:
undetectable		 2l8mA-1y11A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 1y11 HYPOTHETICAL PROTEIN
RV1264/MT1302
(Mycobacterium
tuberculosis) 		4 / 7 THR A 196
ALA A 198
ARG A 214
PRO A 272
 None
 1.00A 2ql8A-1y11A:
undetectable
2ql8B-1y11A:
2.6		 2ql8A-1y11A:
18.48
2ql8B-1y11A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 1y11 HYPOTHETICAL PROTEIN
RV1264/MT1302
(Mycobacterium
tuberculosis) 		4 / 6 THR A 196
ALA A 198
ARG A 214
PRO A 272
 None
 0.95A 2ql8A-1y11A:
undetectable
2ql8B-1y11A:
2.5		 2ql8A-1y11A:
18.48
2ql8B-1y11A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 1y11 HYPOTHETICAL PROTEIN
RV1264/MT1302
(Mycobacterium
tuberculosis) 		4 / 9 ILE A  45
ALA A  29
VAL A  32
GLU A  33
 None
 0.85A 2vufA-1y11A:
1.5		 2vufA-1y11A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 1y11 HYPOTHETICAL PROTEIN
RV1264/MT1302
(Mycobacterium
tuberculosis) 		4 / 7 VAL A 171
THR A  56
LEU A  53
TRP A  34
 1PE  A 409 ( 4.7A)
1PE  A 409 ( 4.7A)
1PE  A 409 ( 4.1A)
None
 1.22A 3arrA-1y11A:
undetectable		 3arrA-1y11A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1y11 HYPOTHETICAL PROTEIN
RV1264/MT1302
(Mycobacterium
tuberculosis) 		5 / 12 SER A  73
LEU A  83
ALA A 111
THR A  65
ALA A  69
 None
 1.06A 4x1kA-1y11A:
undetectable
4x1kB-1y11A:
undetectable		 4x1kA-1y11A:
22.13
4x1kB-1y11A:
21.37