SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y14'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VE3_A_SAMA302_0 (HYPOTHETICAL PROTEIN PH0226)	1y14	DNA-DIRECTED RNA POLYMERASE II 32 KDA POLYPEPTIDE (Saccharomyces cerevisiae)	5 / 12	ALA A 178 GLY A 181 SER A 53 ALA A 49 ILE A 195	None	1.07A	1ve3A-1y14A: undetectable	1ve3A-1y14A: 21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VE3_B_SAMB301_0 (HYPOTHETICAL PROTEIN PH0226)	1y14	DNA-DIRECTED RNA POLYMERASE II 32 KDA POLYPEPTIDE (Saccharomyces cerevisiae)	5 / 12	ALA A 178 GLY A 181 SER A 53 ALA A 49 ILE A 195	None	1.10A	1ve3B-1y14A: undetectable	1ve3B-1y14A: 21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IKK_A_SUZA201_1 (TRANSTHYRETIN)	1y14	DNA-DIRECTED RNA POLYMERASE II 32 KDA POLYPEPTIDE (Saccharomyces cerevisiae)	4 / 8	LEU A 166 ALA A 162 THR A 159 SER A 53	None	0.97A	4ikkA-1y14A: undetectable 4ikkB-1y14A: undetectable	4ikkA-1y14A: 18.78 4ikkB-1y14A: 18.78