SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y17'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 TRP A  67
VAL A  40
TRP A  23
 None
 1.26A 1c4dC-1y17A:
undetectable
1c4dD-1y17A:
undetectable		 1c4dC-1y17A:
9.57
1c4dD-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.32A 1c4dC-1y17A:
undetectable
1c4dD-1y17A:
undetectable		 1c4dC-1y17A:
9.57
1c4dD-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		4 / 5 VAL A 105
GLY A 104
VAL A  66
TRP A  23
 None
 1.22A 1tkqB-1y17A:
undetectable		 1tkqB-1y17A:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		5 / 10 ALA A  52
VAL A 126
VAL A  66
ILE A  68
VAL A  40
 None
 1.09A 2nnjA-1y17A:
undetectable		 2nnjA-1y17A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 VAL A 126
TRP A  23
TRP A  67
 None
 1.23A 2xdcA-1y17A:
undetectable
2xdcB-1y17A:
undetectable		 2xdcA-1y17A:
9.57
2xdcB-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.24A 2xdcA-1y17A:
undetectable
2xdcB-1y17A:
undetectable		 2xdcA-1y17A:
9.57
2xdcB-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 VAL A 126
TRP A  23
TRP A  67
 None
 1.27A 2xdcC-1y17A:
undetectable
2xdcD-1y17A:
undetectable		 2xdcC-1y17A:
9.57
2xdcD-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.04A 2xdcC-1y17A:
undetectable
2xdcD-1y17A:
undetectable		 2xdcC-1y17A:
9.57
2xdcD-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.08A 2xdcE-1y17A:
undetectable
2xdcF-1y17A:
undetectable		 2xdcE-1y17A:
9.57
2xdcF-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 VAL A 126
TRP A  23
TRP A  67
 None
 1.22A 2y5mA-1y17A:
undetectable
2y5mB-1y17A:
undetectable		 2y5mA-1y17A:
9.57
2y5mB-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.05A 2y5mE-1y17A:
undetectable
2y5mF-1y17A:
undetectable		 2y5mE-1y17A:
9.57
2y5mF-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 VAL A 126
TRP A  23
TRP A  67
 None
 1.21A 2y6nA-1y17A:
undetectable
2y6nB-1y17A:
undetectable		 2y6nA-1y17A:
9.57
2y6nB-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.23A 2y6nA-1y17A:
undetectable
2y6nB-1y17A:
undetectable		 2y6nA-1y17A:
9.57
2y6nB-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.03A 2y6nC-1y17A:
undetectable
2y6nD-1y17A:
undetectable		 2y6nC-1y17A:
9.57
2y6nD-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 TRP A  67
VAL A 126
TRP A  23
 None
 1.03A 2y6nE-1y17A:
undetectable
2y6nF-1y17A:
undetectable		 2y6nE-1y17A:
9.57
2y6nF-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		4 / 6 ILE A  55
TYR A  14
ILE A  68
HIS A  65
 None
 0.97A 3eteA-1y17A:
undetectable
3eteE-1y17A:
undetectable		 3eteA-1y17A:
13.08
3eteE-1y17A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		4 / 5 ILE A  55
TYR A  14
ILE A  68
HIS A  65
 None
 0.96A 3eteB-1y17A:
undetectable
3eteC-1y17A:
undetectable		 3eteB-1y17A:
13.08
3eteC-1y17A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		4 / 7 ILE A  68
HIS A  65
ILE A  55
TYR A  14
 None
 0.97A 3eteD-1y17A:
undetectable
3eteF-1y17A:
undetectable		 3eteD-1y17A:
13.08
3eteF-1y17A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 VAL A 126
TRP A  23
TRP A  67
 None
 1.20A 3zq8A-1y17A:
undetectable
3zq8B-1y17A:
undetectable		 3zq8A-1y17A:
9.57
3zq8B-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 TRP A  67
VAL A  40
TRP A  23
 None
 0.89A 3zq8C-1y17A:
undetectable
3zq8D-1y17A:
undetectable		 3zq8C-1y17A:
9.57
3zq8D-1y17A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		5 / 12 GLU A  47
SER A  44
GLN A  73
GLY A  69
LEU A  70
 CA  A1001 (-2.7A)
None
None
None
None
 1.43A 5m50B-1y17A:
undetectable		 5m50B-1y17A:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1y17 ANTICOAGULANT
PROTEIN A
(Deinagkistrodon
acutus) 		3 / 3 VAL A 105
GLU A 115
ILE A  68
 None
 0.36A 6f7lB-1y17A:
undetectable		 6f7lB-1y17A:
12.18