SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y2x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1y2x LECTIN
(Agaricus
bisporus) 		4 / 6 GLY A  52
TYR A  97
GLY A  70
ASN A  94
 None
 1.09A 3e9rA-1y2xA:
undetectable		 3e9rA-1y2xA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 1y2x LECTIN
(Agaricus
bisporus) 		4 / 6 GLY A  52
TYR A  97
GLY A  70
ASN A  94
 None
 1.01A 3e9rC-1y2xA:
undetectable		 3e9rC-1y2xA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1y2x LECTIN
(Agaricus
bisporus) 		3 / 3 ASP A  79
ARG A 103
ALA A 106
 NAG  A 144 (-2.8A)
NAG  A 144 (-4.0A)
NAG  A 144 ( 4.2A)
 0.80A 3mbgC-1y2xA:
undetectable		 3mbgC-1y2xA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1y2x LECTIN
(Agaricus
bisporus) 		3 / 3 GLY A  52
SER A  51
TRP A  77
 None
 0.95A 4e7cD-1y2xA:
undetectable		 4e7cD-1y2xA:
15.65