SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 1y30 HYPOTHETICAL PROTEIN
RV1155
(Mycobacterium
tuberculosis) 		3 / 3 PRO A 135
LEU A  46
ARG A  43
 None
 0.83A 3aqiB-1y30A:
undetectable		 3aqiB-1y30A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_1
(YAEB-LIKE PROTEIN
RPA0152)		 1y30 HYPOTHETICAL PROTEIN
RV1155
(Mycobacterium
tuberculosis) 		4 / 5 SER A  50
ARG A 121
ASP A  97
THR A  89
 None
 1.48A 3okxA-1y30A:
1.7		 3okxA-1y30A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_2
(YAEB-LIKE PROTEIN
RPA0152)		 1y30 HYPOTHETICAL PROTEIN
RV1155
(Mycobacterium
tuberculosis) 		4 / 5 SER A  50
ARG A 121
ASP A  97
THR A  89
 None
 1.48A 3okxB-1y30A:
2.0		 3okxB-1y30A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 1y30 HYPOTHETICAL PROTEIN
RV1155
(Mycobacterium
tuberculosis) 		3 / 3 ASP A  28
ARG A  30
ASP A  64
 None
 0.83A 4fp9A-1y30A:
undetectable		 4fp9A-1y30A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1y30 HYPOTHETICAL PROTEIN
RV1155
(Mycobacterium
tuberculosis) 		3 / 3 SER A 137
ALA A  82
VAL A  81
 None
 0.47A 4o2bA-1y30A:
undetectable		 4o2bA-1y30A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1y30 HYPOTHETICAL PROTEIN
RV1155
(Mycobacterium
tuberculosis) 		3 / 3 SER A 137
ALA A  82
VAL A  81
 None
 0.47A 4o2bC-1y30A:
undetectable		 4o2bC-1y30A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1y30 HYPOTHETICAL PROTEIN
RV1155
(Mycobacterium
tuberculosis) 		3 / 3 SER A 137
ALA A  82
VAL A  81
 None
 0.44A 4x1iA-1y30A:
undetectable		 4x1iA-1y30A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1y30 HYPOTHETICAL PROTEIN
RV1155
(Mycobacterium
tuberculosis) 		3 / 3 SER A 137
ALA A  82
VAL A  81
 None
 0.61A 4x20C-1y30A:
undetectable		 4x20C-1y30A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1y30 HYPOTHETICAL PROTEIN
RV1155
(Mycobacterium
tuberculosis) 		4 / 8 ALA A  82
PRO A 135
LEU A  45
LEU A  46
 None
 1.17A 5dzkd-1y30A:
undetectable
5dzkr-1y30A:
undetectable		 5dzkd-1y30A:
21.30
5dzkr-1y30A:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1y30 HYPOTHETICAL PROTEIN
RV1155
(Mycobacterium
tuberculosis) 		4 / 8 ALA A  82
PRO A 135
LEU A  45
LEU A  46
 None
 1.18A 5dzkF-1y30A:
undetectable
5dzkT-1y30A:
undetectable		 5dzkF-1y30A:
21.30
5dzkT-1y30A:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1y30 HYPOTHETICAL PROTEIN
RV1155
(Mycobacterium
tuberculosis) 		3 / 3 SER A 137
ALA A  82
VAL A  81
 None
 0.44A 5eypA-1y30A:
undetectable		 5eypA-1y30A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 1y30 HYPOTHETICAL PROTEIN
RV1155
(Mycobacterium
tuberculosis) 		4 / 7 PHE A   6
ASP A   7
GLY A 141
HIS A 138
 None
 0.95A 5n9xA-1y30A:
undetectable		 5n9xA-1y30A:
16.07