SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IA4_A_MTXA164_2 (DIHYDROFOLATE REDUCTASE)	1y3j	COPPER-TRANSPORTING ATPASE 1 (Homo sapiens)	4 / 4	ILE A 61 PHE A 66 ILE A 21 THR A 69	None	1.17A	3ia4A-1y3jA: undetectable	3ia4A-1y3jA: 20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OLB_A_TRPA901_0 (PROTEIN ARGONAUTE-2)	1y3j	COPPER-TRANSPORTING ATPASE 1 (Homo sapiens)	3 / 3	VAL A 18 ALA A 43 PHE A 66	None	0.90A	4olbA-1y3jA: 2.6	4olbA-1y3jA: 6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5N_A_IPHA901_0 (PROTEIN ARGONAUTE-2)	1y3j	COPPER-TRANSPORTING ATPASE 1 (Homo sapiens)	3 / 3	VAL A 18 ALA A 43 PHE A 66	None	0.93A	4w5nA-1y3jA: 2.7	4w5nA-1y3jA: 6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OSP_A_ACTA403_0 (CASEIN KINASE II SUBUNIT ALPHA)	1y3j	COPPER-TRANSPORTING ATPASE 1 (Homo sapiens)	4 / 7	VAL A 9 ILE A 7 VAL A 36 ALA A 43	None	0.69A	5ospA-1y3jA: undetectable	5ospA-1y3jA: 16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OSR_A_ACTA402_0 (CASEIN KINASE II SUBUNIT ALPHA)	1y3j	COPPER-TRANSPORTING ATPASE 1 (Homo sapiens)	4 / 7	VAL A 9 ILE A 7 VAL A 36 ALA A 43	None	0.69A	5osrA-1y3jA: undetectable	5osrA-1y3jA: 16.54

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3IA4_A_MTXA164_2","DIHYDROFOLATE REDUCTASE","1y3j","COPPER-TRANSPORTING ATPASE 1","Homo sapiens",4,"ILE A  61;PHE A  66;ILE A  21;THR A  69","None","1.17A","3ia4A-1y3jA:undetectable","3ia4A-1y3jA:20.13"],["4OLB_A_TRPA901_0","PROTEIN ARGONAUTE-2","1y3j","COPPER-TRANSPORTING ATPASE 1","Homo sapiens",3,"VAL A  18;ALA A  43;PHE A  66","None","0.90A","4olbA-1y3jA:2.6","4olbA-1y3jA:6.69"],["4W5N_A_IPHA901_0","PROTEIN ARGONAUTE-2","1y3j","COPPER-TRANSPORTING ATPASE 1","Homo sapiens",3,"VAL A  18;ALA A  43;PHE A  66","None","0.93A","4w5nA-1y3jA:2.7","4w5nA-1y3jA:6.69"],["5OSP_A_ACTA403_0","CASEIN KINASE II SUBUNIT ALPHA","1y3j","COPPER-TRANSPORTING ATPASE 1","Homo sapiens",4,"VAL A   9;ILE A   7;VAL A  36;ALA A  43","None","0.69A","5ospA-1y3jA:undetectable","5ospA-1y3jA:16.54"],["5OSR_A_ACTA402_0","CASEIN KINASE II SUBUNIT ALPHA","1y3j","COPPER-TRANSPORTING ATPASE 1","Homo sapiens",4,"VAL A   9;ILE A   7;VAL A  36;ALA A  43","None","0.69A","5osrA-1y3jA:undetectable","5osrA-1y3jA:16.54"]]