SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y4h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_A_BEZA502_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	1y4h	CYSTEINE PROTEASE INHIBITOR (Staphylococcus aureus)	4 / 6	ASN C 25 ARG C 107 ILE C 42 GLY C 29	SO4 C 462 (-4.0A) None None None	0.94A	1oniA-1y4hC: undetectable 1oniB-1y4hC: undetectable	1oniA-1y4hC: 18.88 1oniB-1y4hC: 18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_D_BEZD508_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	1y4h	CYSTEINE PROTEASE INHIBITOR (Staphylococcus aureus)	4 / 6	ASN C 25 ARG C 107 ILE C 42 GLY C 29	SO4 C 462 (-4.0A) None None None	0.94A	1oniD-1y4hC: undetectable 1oniF-1y4hC: undetectable	1oniD-1y4hC: 18.88 1oniF-1y4hC: 18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_I_BEZI518_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	1y4h	CYSTEINE PROTEASE INHIBITOR (Staphylococcus aureus)	4 / 7	ILE C 42 GLY C 29 ASN C 25 ARG C 107	None None SO4 C 462 (-4.0A) None	0.63A	1oniG-1y4hC: undetectable 1oniI-1y4hC: undetectable	1oniG-1y4hC: 18.88 1oniI-1y4hC: 18.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ONI_A_BEZA502_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","1y4h","CYSTEINE PROTEASE INHIBITOR","Staphylococcus aureus",4,"ASN C  25;ARG C 107;ILE C  42;GLY C  29","SO4 C 462 (-4.0A);None;None;None","0.94A","1oniA-1y4hC:undetectable;1oniB-1y4hC:undetectable","1oniA-1y4hC:18.88;1oniB-1y4hC:18.88"],["1ONI_D_BEZD508_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","1y4h","CYSTEINE PROTEASE INHIBITOR","Staphylococcus aureus",4,"ASN C  25;ARG C 107;ILE C  42;GLY C  29","SO4 C 462 (-4.0A);None;None;None","0.94A","1oniD-1y4hC:undetectable;1oniF-1y4hC:undetectable","1oniD-1y4hC:18.88;1oniF-1y4hC:18.88"],["1ONI_I_BEZI518_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","1y4h","CYSTEINE PROTEASE INHIBITOR","Staphylococcus aureus",4,"ILE C  42;GLY C  29;ASN C  25;ARG C 107","None;None;SO4 C 462 (-4.0A);None","0.63A","1oniG-1y4hC:undetectable;1oniI-1y4hC:undetectable","1oniG-1y4hC:18.88;1oniI-1y4hC:18.88"]]