SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y4m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1y4m HERV-FRD_6P24.1
PROVIRUS ANCESTRAL
ENV POLYPROTEIN
(Homo
sapiens) 		4 / 7 ILE A  85
CSS A  93
GLY A  83
GLY A  84
 None
 0.73A 5a06F-1y4mA:
undetectable		 5a06F-1y4mA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1y4m HERV-FRD_6P24.1
PROVIRUS ANCESTRAL
ENV POLYPROTEIN
(Homo
sapiens) 		4 / 5 ARG A  72
MET A  77
THR A  79
LEU A  78
 None
 1.33A 5w97J-1y4mA:
undetectable		 5w97J-1y4mA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1y4m HERV-FRD_6P24.1
PROVIRUS ANCESTRAL
ENV POLYPROTEIN
(Homo
sapiens) 		4 / 5 ARG A  72
MET A  77
THR A  79
LEU A  78
 None
 1.42A 5z86J-1y4mA:
undetectable		 5z86J-1y4mA:
22.41