SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y5e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		5 / 12 PHE A 109
THR A  82
GLY A 129
GLY A 106
ILE A  91
 None
 1.00A 1nv8B-1y5eA:
2.9		 1nv8B-1y5eA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		5 / 12 PHE A 109
THR A  82
GLY A 129
GLY A 106
ILE A  91
 None
 1.04A 1sg9B-1y5eA:
undetectable		 1sg9B-1y5eA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		5 / 12 PHE A 109
THR A  82
GLY A 106
ILE A  91
ALA A 150
 None
 1.24A 1vq1A-1y5eA:
2.3		 1vq1A-1y5eA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		4 / 7 THR A  78
LEU A  97
VAL A  94
VAL A  53
 None
 1.00A 2cppA-1y5eA:
undetectable		 2cppA-1y5eA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		5 / 12 VAL A  19
CYH A  16
LEU A  77
THR A  78
THR A 163
 None
 1.20A 3a35A-1y5eA:
undetectable		 3a35A-1y5eA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		5 / 12 VAL A  19
CYH A  16
LEU A  77
THR A  78
THR A 163
 None
 1.18A 3a35B-1y5eA:
undetectable		 3a35B-1y5eA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		5 / 12 VAL A  19
CYH A  16
LEU A  77
THR A  78
THR A 163
 None
 1.23A 3a3bA-1y5eA:
undetectable		 3a3bA-1y5eA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		4 / 7 GLY A 133
ASP A  74
TYR A  68
ARG A  15
 None
 1.34A 3arrA-1y5eA:
undetectable		 3arrA-1y5eA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		4 / 7 THR A  90
ILE A  91
ILE A 128
THR A  78
 None
 0.85A 3deuA-1y5eA:
undetectable		 3deuA-1y5eA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		4 / 4 LEU A 149
ALA A 122
ILE A 118
LYS A 153
 None
 1.35A 4eixA-1y5eA:
undetectable		 4eixA-1y5eA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		3 / 3 ASP A  30
ARG A 148
THR A  20
 None
 0.65A 4i13A-1y5eA:
undetectable		 4i13A-1y5eA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		4 / 8 THR A  78
LEU A  97
VAL A  94
VAL A  53
 None
 0.99A 4l4aA-1y5eA:
undetectable		 4l4aA-1y5eA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		4 / 8 THR A  78
LEU A  97
VAL A  94
VAL A  53
 None
 0.95A 4l4eA-1y5eA:
undetectable		 4l4eA-1y5eA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		4 / 8 THR A  78
LEU A  97
VAL A  94
VAL A  53
 None
 0.95A 4l4fA-1y5eA:
0.0		 4l4fA-1y5eA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		3 / 3 ASP A  30
ARG A 148
THR A  20
 None
 0.63A 4p3rA-1y5eA:
undetectable		 4p3rA-1y5eA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		4 / 4 THR A  24
GLY A  81
ASP A  88
SER A  22
 None
 1.29A 4rfqA-1y5eA:
3.3		 4rfqA-1y5eA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		4 / 7 LEU A  77
VAL A  19
GLU A  51
ILE A  91
 None
 0.98A 5jh7C-1y5eA:
undetectable		 5jh7C-1y5eA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		4 / 5 PHE A 138
PHE A 109
LEU A 154
LEU A  36
 None
 1.27A 5veuH-1y5eA:
undetectable		 5veuH-1y5eA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		5 / 9 VAL A  94
VAL A  19
LEU A  97
GLY A  67
THR A  78
 None
 1.36A 6czmB-1y5eA:
undetectable
6czmC-1y5eA:
1.5		 6czmB-1y5eA:
20.87
6czmC-1y5eA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B
(Bacillus
cereus) 		5 / 8 GLY A  67
THR A  78
VAL A  94
VAL A  19
LEU A  97
 None
 1.35A 6czmD-1y5eA:
undetectable
6czmF-1y5eA:
undetectable		 6czmD-1y5eA:
20.87
6czmF-1y5eA:
20.87