SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y76'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
1y76 PROTEIN ASSOCIATED
TO TIGHT JUNCTIONS

(Rattus
norvegicus)
4 / 8 LEU A  13
GLN A  14
LEU A  42
PHE A  38
None
0.91A 1v54C-1y76A:
undetectable
1v54J-1y76A:
undetectable
1v54C-1y76A:
13.03
1v54J-1y76A:
33.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
1y76 PROTEIN ASSOCIATED
TO TIGHT JUNCTIONS

(Rattus
norvegicus)
4 / 7 LEU A  13
GLN A  14
LEU A  42
PHE A  38
None
1.01A 1v55P-1y76A:
undetectable
1v55W-1y76A:
undetectable
1v55P-1y76A:
13.03
1v55W-1y76A:
33.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
1y76 PROTEIN ASSOCIATED
TO TIGHT JUNCTIONS

(Rattus
norvegicus)
4 / 8 LEU A  13
GLN A  14
LEU A  42
PHE A  38
None
0.89A 2dyrC-1y76A:
undetectable
2dyrJ-1y76A:
undetectable
2dyrC-1y76A:
13.03
2dyrJ-1y76A:
33.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
1y76 PROTEIN ASSOCIATED
TO TIGHT JUNCTIONS

(Rattus
norvegicus)
4 / 7 LEU A  13
GLN A  14
LEU A  42
PHE A  38
None
0.90A 2dysC-1y76A:
undetectable
2dysJ-1y76A:
undetectable
2dysC-1y76A:
13.03
2dysJ-1y76A:
33.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
1y76 PROTEIN ASSOCIATED
TO TIGHT JUNCTIONS

(Rattus
norvegicus)
4 / 7 LEU A  13
GLN A  14
LEU A  42
PHE A  38
None
0.95A 2eijC-1y76A:
undetectable
2eijJ-1y76A:
undetectable
2eijC-1y76A:
13.03
2eijJ-1y76A:
33.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1y76 PROTEIN ASSOCIATED
TO TIGHT JUNCTIONS

(Rattus
norvegicus)
4 / 7 LEU A  13
GLN A  14
LEU A  42
PHE A  38
None
0.87A 2zxwC-1y76A:
undetectable
2zxwJ-1y76A:
undetectable
2zxwC-1y76A:
13.03
2zxwJ-1y76A:
33.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1y76 PROTEIN ASSOCIATED
TO TIGHT JUNCTIONS

(Rattus
norvegicus)
4 / 6 LEU A  13
GLN A  14
LEU A  42
PHE A  38
None
0.92A 2zxwP-1y76A:
undetectable
2zxwW-1y76A:
undetectable
2zxwP-1y76A:
13.03
2zxwW-1y76A:
33.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1y76 PROTEIN ASSOCIATED
TO TIGHT JUNCTIONS

(Rattus
norvegicus)
4 / 6 LEU A  13
GLN A  14
LEU A  42
PHE A  38
None
0.85A 3ag1C-1y76A:
undetectable
3ag1J-1y76A:
undetectable
3ag1C-1y76A:
13.03
3ag1J-1y76A:
33.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
1y76 PROTEIN ASSOCIATED
TO TIGHT JUNCTIONS

(Rattus
norvegicus)
4 / 8 LEU A  13
GLN A  14
LEU A  42
PHE A  38
None
0.97A 3asoC-1y76A:
undetectable
3asoJ-1y76A:
undetectable
3asoC-1y76A:
13.03
3asoJ-1y76A:
33.87