SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y7m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1y7m HYPOTHETICAL PROTEIN
BSU14040
(Bacillus
subtilis) 		3 / 3 ILE A  58
ILE A 140
LEU A   2
 None
 0.54A 2prgA-1y7mA:
undetectable		 2prgA-1y7mA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 1y7m HYPOTHETICAL PROTEIN
BSU14040
(Bacillus
subtilis) 		5 / 10 ILE A  15
ASP A  10
ILE A  54
LEU A  48
ILE A 122
 None
 1.09A 3prsA-1y7mA:
undetectable		 3prsA-1y7mA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1y7m HYPOTHETICAL PROTEIN
BSU14040
(Bacillus
subtilis) 		3 / 3 THR A 161
ASN A 163
GLU A  94
 None
 0.66A 3v4tA-1y7mA:
undetectable
3v4tC-1y7mA:
undetectable		 3v4tA-1y7mA:
18.57
3v4tC-1y7mA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1y7m HYPOTHETICAL PROTEIN
BSU14040
(Bacillus
subtilis) 		4 / 8 LEU A 150
VAL A 160
TYR A  56
TYR A  79
 None
 1.03A 3v81A-1y7mA:
2.1		 3v81A-1y7mA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1y7m HYPOTHETICAL PROTEIN
BSU14040
(Bacillus
subtilis) 		4 / 8 ILE A 162
THR A 161
THR A 158
SER A  70
 None
 0.94A 6c06C-1y7mA:
undetectable		 6c06C-1y7mA:
undetectable