SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y7p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CTR_A_TFPA153_1
(CALMODULIN)		 1y7p HYPOTHETICAL PROTEIN
AF1403
(Archaeoglobus
fulgidus) 		5 / 9 GLU A 116
ILE A  90
GLU A 145
ALA A 199
VAL A 148
 None
 1.16A 1ctrA-1y7pA:
undetectable		 1ctrA-1y7pA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 1y7p HYPOTHETICAL PROTEIN
AF1403
(Archaeoglobus
fulgidus) 		6 / 12 LEU A 165
GLY A 169
ILE A  89
SER A 139
LEU A 141
ALA A 144
 None
 1.21A 1v2xA-1y7pA:
3.0		 1v2xA-1y7pA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 1y7p HYPOTHETICAL PROTEIN
AF1403
(Archaeoglobus
fulgidus) 		5 / 9 ILE A 105
ILE A  90
GLY A 103
ALA A 104
THR A 122
 None
 1.26A 2dtjA-1y7pA:
5.5
2dtjB-1y7pA:
5.9		 2dtjA-1y7pA:
22.32
2dtjB-1y7pA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1y7p HYPOTHETICAL PROTEIN
AF1403
(Archaeoglobus
fulgidus) 		5 / 11 LEU A 147
ILE A  90
GLY A  92
ALA A 150
LEU A 175
 None
 1.11A 3n8yA-1y7pA:
undetectable		 3n8yA-1y7pA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1y7p HYPOTHETICAL PROTEIN
AF1403
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 147
ILE A  90
GLY A  92
ALA A 150
LEU A 175
 None
 1.04A 3n8yB-1y7pA:
undetectable		 3n8yB-1y7pA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 1y7p HYPOTHETICAL PROTEIN
AF1403
(Archaeoglobus
fulgidus) 		6 / 12 LEU A 165
ALA A 144
ILE A 203
ILE A  90
VAL A 172
ILE A 170
 None
 1.37A 3ndtB-1y7pA:
undetectable		 3ndtB-1y7pA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1y7p HYPOTHETICAL PROTEIN
AF1403
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 175
GLY A 103
SER A 106
ARG A 110
ILE A 102
 None
 1.23A 4djeA-1y7pA:
undetectable		 4djeA-1y7pA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 1y7p HYPOTHETICAL PROTEIN
AF1403
(Archaeoglobus
fulgidus) 		4 / 7 ARG A  82
GLY A  85
ILE A 118
GLU A 116
 None
 1.10A 4g0vA-1y7pA:
2.5		 4g0vA-1y7pA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1y7p HYPOTHETICAL PROTEIN
AF1403
(Archaeoglobus
fulgidus) 		4 / 8 PRO A 182
SER A 174
VAL A 188
GLY A 155
 None
 0.99A 4mk4A-1y7pA:
3.7		 4mk4A-1y7pA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1y7p HYPOTHETICAL PROTEIN
AF1403
(Archaeoglobus
fulgidus) 		5 / 8 VAL A 146
ILE A 173
ALA A 195
VAL A 120
VAL A  88
 None
 1.41A 5l94A-1y7pA:
undetectable		 5l94A-1y7pA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 1y7p HYPOTHETICAL PROTEIN
AF1403
(Archaeoglobus
fulgidus) 		5 / 10 ILE A 170
ALA A 144
ALA A 199
ILE A 203
ILE A 173
 None
 1.04A 5mvmD-1y7pA:
undetectable
5mvmE-1y7pA:
undetectable		 5mvmD-1y7pA:
15.56
5mvmE-1y7pA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1y7p HYPOTHETICAL PROTEIN
AF1403
(Archaeoglobus
fulgidus) 		4 / 5 ASP A  18
ILE A  61
ASN A  11
TYR A  70
 None
 1.17A 6a93B-1y7pA:
undetectable		 6a93B-1y7pA:
19.85