SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y81'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 1y81 CONSERVED
HYPOTHETICAL PROTEIN
(Pyrococcus
furiosus) 		5 / 12 ALA A  84
PHE A 103
LEU A 104
LEU A  89
PHE A  67
 None
 1.08A 1dtlA-1y81A:
undetectable		 1dtlA-1y81A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 1y81 CONSERVED
HYPOTHETICAL PROTEIN
(Pyrococcus
furiosus) 		5 / 11 VAL A  82
VAL A 109
TYR A 111
GLU A  80
LEU A  75
 None
 1.36A 1t6zB-1y81A:
2.2		 1t6zB-1y81A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 1y81 CONSERVED
HYPOTHETICAL PROTEIN
(Pyrococcus
furiosus) 		4 / 7 GLY A  22
ASN A  23
VAL A  36
ILE A  46
 None
None
UNX  A 406 ( 4.2A)
None
 0.66A 3a2qA-1y81A:
undetectable		 3a2qA-1y81A:
14.50