SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_D_TFPD207_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	1y82	HYPOTHETICAL PROTEIN (Pyrococcus furiosus)	4 / 8	LEU A 63 PHE A 136 PHE A 9 SER A 19	None	0.97A	1wrlC-1y82A: undetectable 1wrlD-1y82A: undetectable	1wrlC-1y82A: 17.90 1wrlD-1y82A: 17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARR_A_PNXA607_1 (CHITINASE A)	1y82	HYPOTHETICAL PROTEIN (Pyrococcus furiosus)	4 / 7	VAL A 35 HIS A 18 THR A 29 LEU A 26	None	1.13A	3arrA-1y82A: undetectable	3arrA-1y82A: 14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RFM_A_CFFA330_1 (ADENOSINE RECEPTOR A2A)	1y82	HYPOTHETICAL PROTEIN (Pyrococcus furiosus)	4 / 7	PHE A 33 MET A 143 MET A 131 ILE A 113	None	1.01A	3rfmA-1y82A: undetectable	3rfmA-1y82A: 16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EYS_A_ACTA402_0 (MCCC FAMILY PROTEIN)	1y82	HYPOTHETICAL PROTEIN (Pyrococcus furiosus)	4 / 6	SER A 11 ASP A 10 ASP A 116 ARG A 119	UNX A 333 ( 3.0A) UNX A 333 ( 3.5A) None None	1.25A	4eysA-1y82A: 2.5	4eysA-1y82A: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5T_A_IPHA905_0 (PROTEIN ARGONAUTE-2)	1y82	HYPOTHETICAL PROTEIN (Pyrococcus furiosus)	4 / 6	ASP A 116 THR A 114 THR A 130 TYR A 120	None None None UNX A 335 (-4.7A)	1.38A	4w5tA-1y82A: 2.4	4w5tA-1y82A: 10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4C_A_IPHA906_0 (PROTEIN ARGONAUTE-2)	1y82	HYPOTHETICAL PROTEIN (Pyrococcus furiosus)	4 / 6	ASP A 116 THR A 114 THR A 130 TYR A 120	None None None UNX A 335 (-4.7A)	1.39A	4z4cA-1y82A: undetectable	4z4cA-1y82A: 10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4F_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	1y82	HYPOTHETICAL PROTEIN (Pyrococcus furiosus)	4 / 6	ASP A 116 THR A 114 THR A 130 TYR A 120	None None None UNX A 335 (-4.7A)	1.34A	4z4fA-1y82A: 2.4	4z4fA-1y82A: 10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4I_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	1y82	HYPOTHETICAL PROTEIN (Pyrococcus furiosus)	4 / 6	ASP A 116 THR A 114 THR A 130 TYR A 120	None None None UNX A 335 (-4.7A)	1.35A	4z4iA-1y82A: 2.5	4z4iA-1y82A: 10.82

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1WRL_D_TFPD207_1","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES;TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","1y82","HYPOTHETICAL PROTEIN","Pyrococcus furiosus",4,"LEU A  63;PHE A 136;PHE A   9;SER A  19","None","0.97A","1wrlC-1y82A:undetectable;1wrlD-1y82A:undetectable","1wrlC-1y82A:17.90;1wrlD-1y82A:17.90"],["3ARR_A_PNXA607_1","CHITINASE A","1y82","HYPOTHETICAL PROTEIN","Pyrococcus furiosus",4,"VAL A  35;HIS A  18;THR A  29;LEU A  26","None","1.13A","3arrA-1y82A:undetectable","3arrA-1y82A:14.53"],["3RFM_A_CFFA330_1","ADENOSINE RECEPTOR A2A","1y82","HYPOTHETICAL PROTEIN","Pyrococcus furiosus",4,"PHE A  33;MET A 143;MET A 131;ILE A 113","None","1.01A","3rfmA-1y82A:undetectable","3rfmA-1y82A:16.72"],["4EYS_A_ACTA402_0","MCCC FAMILY PROTEIN","1y82","HYPOTHETICAL PROTEIN","Pyrococcus furiosus",4,"SER A  11;ASP A  10;ASP A 116;ARG A 119","UNX A 333 ( 3.0A);UNX A 333 ( 3.5A);None;None","1.25A","4eysA-1y82A:2.5","4eysA-1y82A:20.92"],["4W5T_A_IPHA905_0","PROTEIN ARGONAUTE-2","1y82","HYPOTHETICAL PROTEIN","Pyrococcus furiosus",4,"ASP A 116;THR A 114;THR A 130;TYR A 120","None;None;None;UNX A 335 (-4.7A)","1.38A","4w5tA-1y82A:2.4","4w5tA-1y82A:10.82"],["4Z4C_A_IPHA906_0","PROTEIN ARGONAUTE-2","1y82","HYPOTHETICAL PROTEIN","Pyrococcus furiosus",4,"ASP A 116;THR A 114;THR A 130;TYR A 120","None;None;None;UNX A 335 (-4.7A)","1.39A","4z4cA-1y82A:undetectable","4z4cA-1y82A:10.82"],["4Z4F_A_IPHA904_0","PROTEIN ARGONAUTE-2","1y82","HYPOTHETICAL PROTEIN","Pyrococcus furiosus",4,"ASP A 116;THR A 114;THR A 130;TYR A 120","None;None;None;UNX A 335 (-4.7A)","1.34A","4z4fA-1y82A:2.4","4z4fA-1y82A:10.82"],["4Z4I_A_IPHA904_0","PROTEIN ARGONAUTE-2","1y82","HYPOTHETICAL PROTEIN","Pyrococcus furiosus",4,"ASP A 116;THR A 114;THR A 130;TYR A 120","None;None;None;UNX A 335 (-4.7A)","1.35A","4z4iA-1y82A:2.5","4z4iA-1y82A:10.82"]]