SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y89'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_1
(POL POLYPROTEIN)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		5 / 8 ASP A  68
ALA A 146
GLY A 143
GLY A 140
PRO A 167
 PO4  A 239 ( 4.9A)
None
None
PO4  A 241 (-3.3A)
None
 1.26A 1sguA-1y89A:
undetectable		 1sguA-1y89A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		3 / 3 TRP A 134
GLU A 226
TYR A 228
 None
 1.26A 2a3aA-1y89A:
undetectable		 2a3aA-1y89A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		5 / 12 ILE A 102
ARG A 114
PHE A 115
GLY A  37
LEU A 137
 None
 1.05A 2lbdA-1y89A:
undetectable		 2lbdA-1y89A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		4 / 8 ASP A  19
ASP A  20
PHE A   7
LYS A   5
 None
PE5  A 242 (-3.6A)
None
None
 0.97A 4f8hA-1y89A:
undetectable
4f8hB-1y89A:
undetectable		 4f8hA-1y89A:
20.32
4f8hB-1y89A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		4 / 8 ASP A  19
ASP A  20
PHE A   7
LYS A   5
 None
PE5  A 242 (-3.6A)
None
None
 1.00A 4f8hB-1y89A:
undetectable
4f8hC-1y89A:
undetectable		 4f8hB-1y89A:
20.32
4f8hC-1y89A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		4 / 8 ASP A  19
ASP A  20
PHE A   7
LYS A   5
 None
PE5  A 242 (-3.6A)
None
None
 0.97A 4f8hC-1y89A:
undetectable
4f8hD-1y89A:
undetectable		 4f8hC-1y89A:
20.32
4f8hD-1y89A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		4 / 8 ASP A  19
ASP A  20
PHE A   7
LYS A   5
 None
PE5  A 242 (-3.6A)
None
None
 0.97A 4f8hD-1y89A:
undetectable
4f8hE-1y89A:
undetectable		 4f8hD-1y89A:
20.32
4f8hE-1y89A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		4 / 8 PHE A   7
LYS A   5
ASP A  19
ASP A  20
 None
None
None
PE5  A 242 (-3.6A)
 0.98A 4f8hA-1y89A:
undetectable
4f8hE-1y89A:
undetectable		 4f8hA-1y89A:
20.32
4f8hE-1y89A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		5 / 12 ASN A 159
SER A 161
VAL A 174
ILE A 102
CYH A  71
 None
 1.40A 4k36A-1y89A:
1.0		 4k36A-1y89A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		5 / 12 PHE A  64
ILE A  92
VAL A  14
LEU A  48
LEU A  35
 None
 1.31A 4qzuA-1y89A:
undetectable		 4qzuA-1y89A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		3 / 3 LEU A  17
ALA A  18
LEU A 136
 None
 0.42A 5uunB-1y89A:
undetectable		 5uunB-1y89A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 137
GLY A 140
PRO A 214
ALA A 215
ASP A 142
 None
PO4  A 241 (-3.3A)
None
None
PO4  A 241 (-3.6A)
 1.24A 5x6yC-1y89A:
0.4		 5x6yC-1y89A:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 1y89 DEVB PROTEIN
(Vibrio
cholerae) 		3 / 3 LYS A 185
VAL A 131
ASP A 133
 None
 0.64A 6fgdA-1y89A:
undetectable		 6fgdA-1y89A:
20.47