SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y97'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 1y97 THREE PRIME REPAIR
EXONUCLEASE 2
(Homo
sapiens) 		5 / 12 ASP A 155
LEU A 175
TYR A 170
LEU A 208
LEU A 145
 None
 1.31A 1p33A-1y97A:
undetectable		 1p33A-1y97A:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)		 1y97 THREE PRIME REPAIR
EXONUCLEASE 2
(Homo
sapiens) 		5 / 12 ASP A 155
LEU A 175
TYR A 170
LEU A 208
LEU A 145
 None
 1.35A 1p33B-1y97A:
undetectable		 1p33B-1y97A:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1y97 THREE PRIME REPAIR
EXONUCLEASE 2
(Homo
sapiens) 		4 / 7 LEU A 197
LEU A 172
GLU A 207
ARG A 204
 None
 1.01A 2jn3A-1y97A:
undetectable		 2jn3A-1y97A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1y97 THREE PRIME REPAIR
EXONUCLEASE 2
(Homo
sapiens) 		4 / 8 LEU A 131
ILE A 222
ILE A 112
LEU A 127
 None
 0.77A 2o4nB-1y97A:
undetectable		 2o4nB-1y97A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1y97 THREE PRIME REPAIR
EXONUCLEASE 2
(Homo
sapiens) 		5 / 12 ALA A  96
ILE A  27
LEU A  30
GLY A  92
ALA A  91
 None
 0.90A 4nkvB-1y97A:
undetectable		 4nkvB-1y97A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 1y97 THREE PRIME REPAIR
EXONUCLEASE 2
(Homo
sapiens) 		3 / 3 PRO A 125
MET A 225
TYR A 122
 None
 0.97A 4qa0A-1y97A:
undetectable		 4qa0A-1y97A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 1y97 THREE PRIME REPAIR
EXONUCLEASE 2
(Homo
sapiens) 		3 / 3 PRO A 125
MET A 225
TYR A 122
 None
 1.01A 4qa2B-1y97A:
undetectable		 4qa2B-1y97A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 1y97 THREE PRIME REPAIR
EXONUCLEASE 2
(Homo
sapiens) 		5 / 12 LEU A  57
VAL A 143
GLY A 192
LEU A 198
PHE A  10
 None
 1.22A 6a7pA-1y97A:
0.0		 6a7pA-1y97A:
17.41