SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y9g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		4 / 8 GLY A  71
ASP A 189
THR A 129
ASP A  41
 None
FRU  A 801 (-2.7A)
None
FRU  A 801 (-2.7A)
 0.85A 1m4iA-1y9gA:
undetectable		 1m4iA-1y9gA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		5 / 10 GLU A  99
ARG A  91
ALA A 154
LEU A  88
GLY A 104
 None
 1.28A 1mjqG-1y9gA:
undetectable
1mjqH-1y9gA:
undetectable		 1mjqG-1y9gA:
11.35
1mjqH-1y9gA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		3 / 3 TRP A  70
PHE A  55
TRP A 163
 None
 1.41A 1r15H-1y9gA:
undetectable		 1r15H-1y9gA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		5 / 10 LEU A 480
ALA A 516
VAL A 491
LEU A 448
PHE A 412
 None
 1.19A 1rlbE-1y9gA:
undetectable		 1rlbE-1y9gA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUF_B_AZ1B503_1
(DIAMINOPIMELATE
DECARBOXYLASE)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		4 / 6 GLU A  83
SER A  33
ARG A  27
TYR A  22
 None
 1.23A 1tufA-1y9gA:
undetectable
1tufB-1y9gA:
undetectable		 1tufA-1y9gA:
22.35
1tufB-1y9gA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1URM_A_BEZA201_0
(PEROXIREDOXIN 5)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		5 / 9 THR A 420
GLY A 519
SER A 419
LEU A 436
PHE A 447
 None
 1.39A 1urmA-1y9gA:
undetectable		 1urmA-1y9gA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		4 / 8 PHE A 441
PHE A 447
ALA A 516
LEU A 392
 None
 0.96A 1x8vA-1y9gA:
undetectable		 1x8vA-1y9gA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		5 / 12 ASP A 307
GLY A 309
ASP A 311
ILE A 482
PRO A 371
 None
 0.87A 2nmyA-1y9gA:
undetectable		 2nmyA-1y9gA:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		4 / 5 PHE A 280
PHE A 230
TRP A 240
GLY A 244
 None
 1.27A 2qmzA-1y9gA:
undetectable
2qmzB-1y9gA:
undetectable		 2qmzA-1y9gA:
18.57
2qmzB-1y9gA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		3 / 3 VAL A 259
ASN A 304
TRP A 305
 None
 1.08A 2y00B-1y9gA:
undetectable		 2y00B-1y9gA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		4 / 5 GLN A  57
PHE A  56
LEU A  89
PHE A  93
 FRU  A 801 (-3.6A)
None
None
NAG  A1001 (-3.8A)
 1.49A 3ablC-1y9gA:
undetectable
3ablJ-1y9gA:
undetectable		 3ablC-1y9gA:
20.90
3ablJ-1y9gA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		4 / 7 ASP A 509
SER A 507
SER A 453
ASP A 449
 NAG  A3001 ( 4.2A)
None
None
None
 1.02A 3bc9A-1y9gA:
undetectable		 3bc9A-1y9gA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		4 / 5 VAL A 203
VAL A 204
THR A 129
THR A 217
 None
 1.07A 3bjwG-1y9gA:
undetectable		 3bjwG-1y9gA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		4 / 5 VAL A 203
VAL A 204
THR A 129
THR A 217
 None
 1.10A 3bjwC-1y9gA:
undetectable		 3bjwC-1y9gA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		5 / 12 ASP A 307
GLY A 309
ASP A 311
ILE A 482
PRO A 371
 None
 0.94A 3el4A-1y9gA:
undetectable		 3el4A-1y9gA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		5 / 10 VAL A 525
ALA A 424
ILE A 423
LEU A 410
PHE A 421
 None
 1.21A 3fl9A-1y9gA:
undetectable		 3fl9A-1y9gA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		5 / 10 VAL A 525
ALA A 424
ILE A 423
LEU A 410
PHE A 421
 None
 1.14A 3fl9F-1y9gA:
undetectable		 3fl9F-1y9gA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		4 / 6 VAL A 327
SER A  75
LEU A 124
LEU A 321
 None
 0.99A 3kk6A-1y9gA:
undetectable		 3kk6A-1y9gA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		4 / 8 PHE A 406
GLY A 403
ILE A 504
PHE A 483
 None
 0.98A 3ko0O-1y9gA:
undetectable
3ko0Q-1y9gA:
undetectable		 3ko0O-1y9gA:
12.19
3ko0Q-1y9gA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		4 / 6 GLY A  28
TRP A 346
ASP A 485
THR A 405
 None
 1.14A 3vqrA-1y9gA:
undetectable		 3vqrA-1y9gA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		3 / 3 TYR A 385
ARG A 387
SER A 386
 None
 1.07A 4dr2I-1y9gA:
undetectable
4dr2J-1y9gA:
undetectable		 4dr2I-1y9gA:
13.93
4dr2J-1y9gA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		3 / 3 SER A 130
TYR A 132
ASP A 167
 None
 0.90A 4rp8C-1y9gA:
undetectable		 4rp8C-1y9gA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		5 / 12 GLY A 468
LEU A 470
VAL A 525
GLY A 493
THR A 499
 None
 1.11A 5hg0A-1y9gA:
undetectable		 5hg0A-1y9gA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		5 / 12 GLY A 468
LEU A 470
VAL A 525
GLY A 493
THR A 499
 None
 1.09A 5hg0B-1y9gA:
undetectable		 5hg0B-1y9gA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA304_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1y9g EXO-INULINASE
(Aspergillus
awamori) 		4 / 4 ARG A 354
THR A 501
GLY A 330
PHE A 312
 None
 1.27A 5uunA-1y9gA:
0.0		 5uunA-1y9gA:
20.43