SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y9j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 1y9j SEC1 FAMILY DOMAIN
CONTAINING PROTEIN 1
(Rattus
norvegicus) 		4 / 8 LEU A  41
PHE A  86
ARG A  45
GLY A  47
 None
 0.94A 2vdbA-1y9jA:
undetectable		 2vdbA-1y9jA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1y9j SEC1 FAMILY DOMAIN
CONTAINING PROTEIN 1
(Rattus
norvegicus) 		4 / 8 LEU A  22
LYS A  39
TYR A  43
LEU A  60
 None
 0.97A 3v81A-1y9jA:
undetectable		 3v81A-1y9jA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 1y9j SEC1 FAMILY DOMAIN
CONTAINING PROTEIN 1
(Rattus
norvegicus) 		4 / 7 LEU A  22
LYS A  39
TYR A  43
LEU A  60
 None
 0.93A 4b3qA-1y9jA:
undetectable		 4b3qA-1y9jA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1y9j SEC1 FAMILY DOMAIN
CONTAINING PROTEIN 1
(Rattus
norvegicus) 		4 / 8 LEU A  22
LYS A  39
TYR A  43
LEU A  60
 None
 1.08A 4q0bA-1y9jA:
undetectable		 4q0bA-1y9jA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 1y9j SEC1 FAMILY DOMAIN
CONTAINING PROTEIN 1
(Rattus
norvegicus) 		4 / 8 ASN A 112
MET A  21
PHE A 113
TYR A 145
 None
 1.45A 4v2zB-1y9jA:
undetectable		 4v2zB-1y9jA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 1y9j SEC1 FAMILY DOMAIN
CONTAINING PROTEIN 1
(Rattus
norvegicus) 		4 / 8 ASN A 112
MET A  21
PHE A 113
TYR A 145
 None
 1.36A 4v30B-1y9jA:
undetectable		 4v30B-1y9jA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1y9j SEC1 FAMILY DOMAIN
CONTAINING PROTEIN 1
(Rattus
norvegicus) 		4 / 5 TYR A  85
SER A 108
ALA A  83
THR A  66
 None
 1.33A 5n0tA-1y9jA:
2.3		 5n0tA-1y9jA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1y9j SEC1 FAMILY DOMAIN
CONTAINING PROTEIN 1
(Rattus
norvegicus) 		4 / 8 ARG A  20
ILE A  51
PHE A  86
TYR A 106
 None
 0.89A 5nooD-1y9jA:
undetectable		 5nooD-1y9jA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 1y9j SEC1 FAMILY DOMAIN
CONTAINING PROTEIN 1
(Rattus
norvegicus) 		5 / 11 PRO A  89
ILE A  50
VAL A 141
MET A  21
LEU A  22
 None
 1.16A 5tiyA-1y9jA:
0.0		 5tiyA-1y9jA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 1y9j SEC1 FAMILY DOMAIN
CONTAINING PROTEIN 1
(Rattus
norvegicus) 		5 / 10 TYR A 145
ILE A  10
ASN A 112
ALA A  17
LEU A  18
 None
 1.22A 5y7pB-1y9jA:
undetectable		 5y7pB-1y9jA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 1y9j SEC1 FAMILY DOMAIN
CONTAINING PROTEIN 1
(Rattus
norvegicus) 		5 / 10 TYR A 145
ILE A  10
ASN A 112
ALA A  17
LEU A  18
 None
 1.26A 5y7pD-1y9jA:
undetectable		 5y7pD-1y9jA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 1y9j SEC1 FAMILY DOMAIN
CONTAINING PROTEIN 1
(Rattus
norvegicus) 		5 / 10 TYR A 145
ILE A  10
ASN A 112
ALA A  17
LEU A  18
 None
 1.23A 5y7pG-1y9jA:
undetectable		 5y7pG-1y9jA:
19.14