SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1y9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 1y9k IAA
ACETYLTRANSFERASE
(Bacillus
cereus) 		4 / 7 VAL A  46
LEU A  17
LEU A  71
VAL A   3
 None
 0.80A 1jgsA-1y9kA:
undetectable		 1jgsA-1y9kA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1y9k IAA
ACETYLTRANSFERASE
(Bacillus
cereus) 		3 / 3 LYS A  79
ILE A  65
THR A  87
 None
 0.83A 1rx3A-1y9kA:
undetectable		 1rx3A-1y9kA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 1y9k IAA
ACETYLTRANSFERASE
(Bacillus
cereus) 		5 / 10 SER A 106
ALA A  66
LEU A  17
LEU A  20
LEU A 110
 None
 1.07A 2bxqA-1y9kA:
undetectable		 2bxqA-1y9kA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1y9k IAA
ACETYLTRANSFERASE
(Bacillus
cereus) 		5 / 12 LEU A  81
TYR A  50
GLY A  48
GLY A  77
HIS A  83
 None
 1.03A 3ou6B-1y9kA:
undetectable		 3ou6B-1y9kA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 1y9k IAA
ACETYLTRANSFERASE
(Bacillus
cereus) 		3 / 3 LYS A  79
ILE A  65
THR A  87
 None
 0.83A 4gh8A-1y9kA:
undetectable		 4gh8A-1y9kA:
22.09