SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yb0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 GLU A 105
TYR A 101
TYR A 102
ASN A  30
HIS A 139
 None
 1.08A 1x70A-1yb0A:
2.0		 1x70A-1yb0A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 GLU A 105
TYR A 101
TYR A 102
ASN A  30
HIS A 139
 None
 1.08A 1x70B-1yb0A:
undetectable		 1x70B-1yb0A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		4 / 7 TYR A 101
VAL A 109
VAL A  28
VAL A  89
 None
 1.02A 2qbnA-1yb0A:
undetectable		 2qbnA-1yb0A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		4 / 5 ALA A  72
GLY A  82
CYH A  75
HIS A  29
 None
None
None
ZN  A 160 ( 3.2A)
 1.23A 2yldA-1yb0A:
undetectable		 2yldA-1yb0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		4 / 5 ALA A  72
GLY A  82
CYH A  75
HIS A  29
 None
None
None
ZN  A 160 ( 3.2A)
 1.27A 2ylgA-1yb0A:
undetectable		 2ylgA-1yb0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 GLU A 105
TYR A 101
TYR A 102
ASN A  30
HIS A 139
 None
 1.05A 3bjmA-1yb0A:
2.3		 3bjmA-1yb0A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 GLU A 105
TYR A 101
TYR A 102
ASN A  30
HIS A 139
 None
 1.11A 3bjmB-1yb0A:
2.0		 3bjmB-1yb0A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 11 ALA A 104
ASP A  59
ASP A  58
GLY A  97
ILE A  91
 None
 1.15A 3ektD-1yb0A:
undetectable		 3ektD-1yb0A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 GLU A 105
TYR A 101
TYR A 102
ASN A  30
HIS A 139
 None
 1.09A 3g0bA-1yb0A:
2.1		 3g0bA-1yb0A:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 GLU A 105
TYR A 101
TYR A 102
ASN A  30
HIS A 139
 None
 1.11A 3g0bB-1yb0A:
2.1		 3g0bB-1yb0A:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 GLU A 105
TYR A 101
TYR A 102
ASN A  30
HIS A 139
 None
 1.10A 3g0bC-1yb0A:
2.2		 3g0bC-1yb0A:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 GLU A 105
TYR A 101
TYR A 102
ASN A  30
HIS A 139
 None
 1.10A 3g0bD-1yb0A:
2.0		 3g0bD-1yb0A:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 ALA A 104
ASP A  59
ASP A  58
GLY A  97
ILE A  91
 None
 0.99A 3mwsA-1yb0A:
undetectable		 3mwsA-1yb0A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 GLU A 105
TYR A 101
TYR A 102
ASN A  30
HIS A 139
 None
 1.15A 3w2tA-1yb0A:
2.2		 3w2tA-1yb0A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 GLU A 105
TYR A 101
TYR A 102
ASN A  30
HIS A 139
 None
 1.12A 3w2tB-1yb0A:
undetectable		 3w2tB-1yb0A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		4 / 5 ALA A  72
GLY A  82
CYH A  75
HIS A  29
 None
None
None
ZN  A 160 ( 3.2A)
 1.23A 3zwiA-1yb0A:
undetectable		 3zwiA-1yb0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CIP_A_ASCA130_0
(CYTOCHROME C')		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		4 / 4 ALA A  72
GLY A  82
CYH A  75
HIS A  29
 None
None
None
ZN  A 160 ( 3.2A)
 1.23A 4cipA-1yb0A:
undetectable		 4cipA-1yb0A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_D_SAMD800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 10 ILE A  66
ALA A  72
GLU A  50
GLY A  80
ASN A  79
 None
 1.35A 4e47D-1yb0A:
undetectable		 4e47D-1yb0A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J83_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 11 ILE A  66
ALA A  72
GLU A  50
GLY A  80
ASN A  79
 None
 1.37A 4j83A-1yb0A:
0.0		 4j83A-1yb0A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		3 / 3 ILE A 151
MET A 141
ARG A 146
 None
 0.85A 4lnwA-1yb0A:
undetectable		 4lnwA-1yb0A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		3 / 3 ILE A 151
MET A 141
ARG A 146
 None
 0.84A 4lnxA-1yb0A:
undetectable		 4lnxA-1yb0A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 ALA A 104
ASP A  59
ASP A  58
GLY A  97
ILE A  91
 None
 1.01A 4njvA-1yb0A:
undetectable		 4njvA-1yb0A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSL_A_ASCA202_0
(CYTOCHROME C')		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		4 / 4 ALA A  72
GLY A  82
CYH A  75
HIS A  29
 None
None
None
ZN  A 160 ( 3.2A)
 1.25A 5jslA-1yb0A:
undetectable		 5jslA-1yb0A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		4 / 5 ALA A  72
GLY A  82
CYH A  75
HIS A  29
 None
None
None
ZN  A 160 ( 3.2A)
 1.25A 5jt4A-1yb0A:
undetectable		 5jt4A-1yb0A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1yb0 PROPHAGE LAMBDABA02,
N-ACETYLMURAMOYL-L-A
LANINE AMIDASE,
FAMILY 2
(Bacillus
anthracis) 		5 / 12 GLU A 105
TYR A 101
TYR A 102
ASN A  30
HIS A 139
 None
 1.12A 6b1eB-1yb0A:
undetectable		 6b1eB-1yb0A:
12.59