SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ybf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 207
LEU A 206
ILE A  92
GLY A 239
LEU A 236
 None
 1.11A 1g50B-1ybfA:
undetectable		 1g50B-1ybfA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 207
LEU A 206
ILE A  92
GLY A 239
LEU A 236
 None
 1.11A 1g50C-1ybfA:
undetectable		 1g50C-1ybfA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A  98
VAL A 184
MET A 186
GLU A 187
SER A 209
 None
 0.68A 1jdvE-1ybfA:
25.1
1jdvF-1ybfA:
24.6		 1jdvE-1ybfA:
25.66
1jdvF-1ybfA:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 8 GLY A  98
VAL A 184
MET A 186
GLU A 187
SER A 209
 None
 0.74A 1pk7B-1ybfA:
24.7		 1pk7B-1ybfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 GLY A  98
VAL A 184
MET A 186
GLU A 187
SER A 209
 None
 0.62A 1pk7C-1ybfA:
24.8		 1pk7C-1ybfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 MET A  71
GLY A  98
VAL A 184
MET A 186
SER A 209
 None
 0.88A 1pk7C-1ybfA:
24.8		 1pk7C-1ybfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 GLY A  98
VAL A 184
MET A 186
GLU A 187
SER A 209
 None
 0.61A 1pk9A-1ybfA:
24.8		 1pk9A-1ybfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 MET A  71
GLY A  98
VAL A 184
MET A 186
SER A 209
 None
 0.87A 1pk9A-1ybfA:
24.8		 1pk9A-1ybfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLY A  98
VAL A 184
MET A 186
GLU A 187
SER A 209
 None
 0.60A 1pk9C-1ybfA:
24.8		 1pk9C-1ybfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 MET A  71
GLY A  98
VAL A 184
MET A 186
SER A 209
 None
 0.83A 1pk9C-1ybfA:
24.8		 1pk9C-1ybfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 10 GLY A  98
THR A 161
VAL A 184
MET A 186
GLU A 187
SER A 209
 None
 0.68A 1z35A-1ybfA:
24.5		 1z35A-1ybfA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 10 MET A  71
GLY A  98
THR A 161
VAL A 184
MET A 186
SER A 209
 None
 0.90A 1z35A-1ybfA:
24.5		 1z35A-1ybfA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 MET A  71
GLY A  98
VAL A 184
MET A 186
SER A 209
 None
 0.95A 1z37A-1ybfA:
24.5		 1z37A-1ybfA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 207
LEU A 206
ILE A  92
GLY A 239
LEU A 236
 None
 1.07A 2j7xA-1ybfA:
undetectable		 2j7xA-1ybfA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 206
LEU A 238
LEU A 139
THR A 188
PHE A  93
 None
 1.42A 2oaxA-1ybfA:
undetectable		 2oaxA-1ybfA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 206
VAL A 158
GLY A 183
GLY A 156
 None
 0.77A 2wd9A-1ybfA:
2.2		 2wd9A-1ybfA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 LEU A 206
VAL A 158
GLY A 183
GLY A 156
 None
 0.77A 2wd9B-1ybfA:
2.2		 2wd9B-1ybfA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 207
LEU A 206
ILE A  92
GLY A 239
LEU A 236
 None
 1.07A 2yjaB-1ybfA:
undetectable		 2yjaB-1ybfA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 PHE A  34
ASN A  33
PHE A  93
 None
 0.95A 2zbuD-1ybfA:
2.8		 2zbuD-1ybfA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 6 VAL A 158
LEU A  30
ILE A  79
ALA A 204
LEU A 206
 None
 1.29A 3kk6B-1ybfA:
undetectable		 3kk6B-1ybfA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 207
LEU A 206
ILE A  92
GLY A 239
LEU A 236
 None
 0.97A 3q95A-1ybfA:
undetectable		 3q95A-1ybfA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		6 / 11 MET A  71
GLY A  98
VAL A 184
MET A 186
GLU A 187
SER A 209
 None
 0.93A 3uawA-1ybfA:
24.0		 3uawA-1ybfA:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLY A  98
VAL A 184
MET A 186
GLU A 187
SER A 209
 None
 0.68A 4d9hA-1ybfA:
23.3		 4d9hA-1ybfA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 MET A  71
GLY A  98
VAL A 184
MET A 186
SER A 209
 None
 0.96A 4d9hA-1ybfA:
23.3		 4d9hA-1ybfA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 10 MET A  71
GLY A  98
VAL A 184
MET A 186
SER A 209
 None
 0.97A 4da7A-1ybfA:
23.0		 4da7A-1ybfA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A  91
LEU A 191
ALA A  76
LEU A  82
LEU A  83
 None
 1.18A 4i1rA-1ybfA:
undetectable		 4i1rA-1ybfA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 207
LEU A 206
ILE A  92
GLY A 239
LEU A 236
 None
 1.12A 4j26A-1ybfA:
undetectable		 4j26A-1ybfA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PHE A  25
GLN A  19
GLY A  51
THR A  54
 None
 0.99A 4k87A-1ybfA:
undetectable		 4k87A-1ybfA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 207
LEU A 206
ILE A  92
GLY A 239
LEU A 236
 None
 1.05A 5dxbB-1ybfA:
undetectable		 5dxbB-1ybfA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 207
LEU A 206
ILE A  92
GLY A 239
LEU A 236
 None
 1.08A 5gtrA-1ybfA:
undetectable		 5gtrA-1ybfA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLY A  98
VAL A 184
MET A 186
GLU A 187
SER A 209
 None
 0.61A 5i3cC-1ybfA:
24.9		 5i3cC-1ybfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 MET A  71
GLY A  98
VAL A 184
MET A 186
SER A 209
 None
 0.87A 5i3cC-1ybfA:
24.9		 5i3cC-1ybfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 156
GLU A 167
ALA A 189
SER A 209
ILE A 208
 None
 1.07A 5ih0A-1ybfA:
undetectable		 5ih0A-1ybfA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 190
SER A 122
TYR A 125
 None
 0.86A 5jsdA-1ybfA:
undetectable		 5jsdA-1ybfA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 190
SER A 122
TYR A 125
 None
 0.87A 5jsdB-1ybfA:
undetectable		 5jsdB-1ybfA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 190
SER A 122
TYR A 125
 None
 0.86A 5jsdC-1ybfA:
undetectable		 5jsdC-1ybfA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 190
SER A 122
TYR A 125
 None
 0.87A 5jseA-1ybfA:
undetectable		 5jseA-1ybfA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 190
SER A 122
TYR A 125
 None
 0.87A 5jseB-1ybfA:
undetectable		 5jseB-1ybfA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 THR A 190
SER A 122
TYR A 125
 None
 0.87A 5jseC-1ybfA:
undetectable		 5jseC-1ybfA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 102
GLY A  99
GLY A  98
VAL A 184
TRP A 166
 None
 1.17A 5uc1A-1ybfA:
undetectable		 5uc1A-1ybfA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1ybf AMP NUCLEOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY A 118
VAL A 158
SER A  73
ALA A  76
 None
 0.63A 6hu9H-1ybfA:
undetectable
6hu9e-1ybfA:
undetectable		 6hu9H-1ybfA:
16.23
6hu9e-1ybfA:
18.71