SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ybm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		4 / 8 VAL A 211
VAL A  74
LEU A  76
VAL A 129
 None
 0.75A 2zujA-1ybmA:
undetectable		 2zujA-1ybmA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		4 / 6 GLY A 132
SER A  78
ILE A 172
GLU A 159
 NAP  A 400 (-4.4A)
NAP  A 400 (-3.3A)
None
None
 0.85A 3a7eA-1ybmA:
6.0		 3a7eA-1ybmA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		5 / 12 GLY A  11
GLY A  14
ARG A  38
ASP A  56
ILE A  57
 NAP  A 400 ( 3.8A)
NAP  A 400 (-3.2A)
NAP  A 400 (-3.6A)
NAP  A 400 (-3.5A)
NAP  A 400 (-3.7A)
 0.88A 3ihtA-1ybmA:
undetectable		 3ihtA-1ybmA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		5 / 12 GLY A  11
SER A  39
ASP A  56
ILE A  57
THR A  58
 NAP  A 400 ( 3.8A)
NAP  A 400 ( 4.4A)
NAP  A 400 (-3.5A)
NAP  A 400 (-3.7A)
NAP  A 400 ( 4.5A)
 0.72A 3iv6A-1ybmA:
6.1		 3iv6A-1ybmA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		4 / 6 ILE A  19
ILE A  57
GLY A  11
VAL A 129
 None
NAP  A 400 (-3.7A)
NAP  A 400 ( 3.8A)
None
 0.90A 3n3iA-1ybmA:
undetectable		 3n3iA-1ybmA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		5 / 12 ALA A  60
PHE A  67
THR A  77
ILE A  75
LEU A  73
 None
None
NAP  A 400 (-4.5A)
None
None
 1.13A 4nx7A-1ybmA:
undetectable		 4nx7A-1ybmA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		5 / 12 PHE A 246
ILE A 172
ALA A 215
THR A 239
LEU A 228
 None
 1.33A 4qynA-1ybmA:
undetectable		 4qynA-1ybmA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		5 / 12 PHE A 246
ILE A 172
ALA A 215
THR A 239
LEU A 228
 None
 1.39A 4qzuA-1ybmA:
undetectable		 4qzuA-1ybmA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		4 / 7 VAL A  20
ILE A 172
ALA A 215
ILE A 171
 None
 0.52A 4uxqA-1ybmA:
undetectable		 4uxqA-1ybmA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		4 / 7 ASP A 227
ARG A 173
GLY A 132
GLU A 159
 None
None
NAP  A 400 (-4.4A)
None
 1.11A 5btfA-1ybmA:
undetectable
5btfC-1ybmA:
undetectable
5btfD-1ybmA:
2.8		 5btfA-1ybmA:
19.96
5btfC-1ybmA:
19.96
5btfD-1ybmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		5 / 12 VAL A  74
LEU A 216
ALA A 119
GLY A  35
LEU A  24
 None
 1.04A 5jw1A-1ybmA:
undetectable		 5jw1A-1ybmA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		3 / 3 LYS A 222
LEU A 245
ILE A 172
 None
 0.78A 5kc4A-1ybmA:
undetectable		 5kc4A-1ybmA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		5 / 12 GLY A 135
GLY A 132
GLU A 159
VAL A 211
ASP A 227
 None
NAP  A 400 (-4.4A)
None
None
None
 0.75A 5wz2C-1ybmA:
4.7		 5wz2C-1ybmA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 1ybm UNKNOWN PROTEIN
AT5G02240
(Arabidopsis
thaliana) 		5 / 12 THR A  58
THR A  77
LEU A 146
PRO A 105
PHE A  99
 NAP  A 400 ( 4.5A)
NAP  A 400 (-4.5A)
None
None
None
 1.37A 5ybbB-1ybmA:
5.0		 5ybbB-1ybmA:
19.48