SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ybt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1ybt HYDROLASE,
ALPHA/BETA HYDROLASE
FOLD FAMILY
(Mycobacterium
tuberculosis) 		3 / 3 ARG A 430
VAL A 422
GLY A 379
 None
 0.53A 2avvE-1ybtA:
undetectable		 2avvE-1ybtA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 1ybt HYDROLASE,
ALPHA/BETA HYDROLASE
FOLD FAMILY
(Mycobacterium
tuberculosis) 		5 / 10 HIS A 331
ALA A 358
GLY A 379
ILE A 380
ALA A 350
 None
 1.32A 5vyhA-1ybtA:
undetectable		 5vyhA-1ybtA:
16.29