SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1yc6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		5 / 8 GLU A  55
ILE A  61
LEU A 156
ALA A 166
VAL A 162
 None
 1.11A 1a29A-1yc6A:
undetectable		 1a29A-1yc6A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		3 / 3 LEU A  73
PRO A  74
LEU A  77
 None
 0.44A 1hrkA-1yc6A:
undetectable		 1hrkA-1yc6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		4 / 4 VAL A  87
ALA A 144
LEU A 152
PHE A 141
 None
 1.05A 1q97B-1yc6A:
undetectable		 1q97B-1yc6A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		3 / 3 SER A 128
VAL A 167
LEU A  96
 None
 0.64A 1yajG-1yc6A:
undetectable		 1yajG-1yc6A:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		5 / 11 LEU A 171
LEU A  73
LEU A 152
ASN A 151
VAL A  87
 None
 1.21A 3e22B-1yc6A:
undetectable		 3e22B-1yc6A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		5 / 11 LEU A 171
LEU A  73
LEU A 152
ASN A 151
VAL A  87
 None
 1.23A 3e22D-1yc6A:
undetectable		 3e22D-1yc6A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		5 / 11 LEU A 171
LEU A 152
ASN A 151
ALA A 144
VAL A  87
 None
 1.04A 3e22D-1yc6A:
undetectable		 3e22D-1yc6A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		6 / 12 VAL A  90
LEU A  73
ILE A  71
LEU A 152
ASP A 148
PHE A 141
 None
 1.18A 3gp0A-1yc6A:
undetectable		 3gp0A-1yc6A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		5 / 12 ALA A 158
LEU A 156
ASN A  67
MET A  69
ALA A 166
 None
 1.16A 3ut5D-1yc6A:
undetectable		 3ut5D-1yc6A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		3 / 3 LEU A  73
PRO A  74
LEU A  77
 None
 0.48A 3w1wB-1yc6A:
undetectable		 3w1wB-1yc6A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		3 / 3 HIS A 175
VAL A 108
LEU A 171
 None
 0.77A 4m2vA-1yc6A:
undetectable		 4m2vA-1yc6A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_2
(TUBULIN BETA CHAIN)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		5 / 12 ALA A 158
LEU A 156
ASN A  67
MET A  69
ALA A 166
 None
 1.08A 4x1iB-1yc6A:
undetectable		 4x1iB-1yc6A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1yc6 COAT PROTEIN
(Brome
mosaic
virus) 		4 / 8 ALA A 144
VAL A  87
ILE A  71
VAL A 108
 None
 0.77A 5nujA-1yc6A:
undetectable		 5nujA-1yc6A:
16.23