SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ycd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1ycd HYPOTHETICAL 27.3
KDA PROTEIN IN
AAP1-SMF2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 5 PHE A  10
TYR A  41
VAL A 220
VAL A 231
 None
 1.22A 1dz6B-1ycdA:
0.0		 1dz6B-1ycdA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1ycd HYPOTHETICAL 27.3
KDA PROTEIN IN
AAP1-SMF2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 9 PHE A  10
TYR A  41
VAL A 220
ILE A 227
VAL A 231
 None
 1.21A 1gebA-1ycdA:
undetectable		 1gebA-1ycdA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1ycd HYPOTHETICAL 27.3
KDA PROTEIN IN
AAP1-SMF2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 115
ILE A 157
ARG A 162
TYR A 142
 None
 1.49A 1rk3A-1ycdA:
0.0		 1rk3A-1ycdA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1ycd HYPOTHETICAL 27.3
KDA PROTEIN IN
AAP1-SMF2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 7 LYS A 200
ASN A 203
PRO A 169
ALA A 201
 None
 1.08A 2ejgA-1ycdA:
undetectable		 2ejgA-1ycdA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1ycd HYPOTHETICAL 27.3
KDA PROTEIN IN
AAP1-SMF2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 7 LYS A 200
ASN A 203
PRO A 169
ALA A 201
 None
 1.19A 2ejgB-1ycdA:
undetectable		 2ejgB-1ycdA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1ycd HYPOTHETICAL 27.3
KDA PROTEIN IN
AAP1-SMF2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 11 ALA A  44
PHE A  75
SER A  87
PHE A 161
VAL A  93
 None
 1.46A 4eilA-1ycdA:
undetectable		 4eilA-1ycdA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 1ycd HYPOTHETICAL 27.3
KDA PROTEIN IN
AAP1-SMF2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 7 PHE A  75
SER A 164
ILE A 157
PHE A 165
 None
 1.06A 4uymA-1ycdA:
undetectable		 4uymA-1ycdA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ycd HYPOTHETICAL 27.3
KDA PROTEIN IN
AAP1-SMF2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 144
SER A 117
LEU A  11
PHE A  75
LEU A 194
 None
 1.42A 4xldA-1ycdA:
0.0		 4xldA-1ycdA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1ycd HYPOTHETICAL 27.3
KDA PROTEIN IN
AAP1-SMF2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 154
HIS A 151
ARG A 156
 None
 0.97A 5uunA-1ycdA:
undetectable		 5uunA-1ycdA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 1ycd HYPOTHETICAL 27.3
KDA PROTEIN IN
AAP1-SMF2 INTERGENIC
REGION
(Saccharomyces
cerevisiae) 		4 / 5 PRO A   6
VAL A  37
GLY A 108
VAL A 135
 None
 1.11A 6ak3B-1ycdA:
undetectable		 6ak3B-1ycdA:
15.06